Figure 2.

Cytokine production and mannose receptor-mediated phagocytic capacity of monocyte-derived cell populations. (A) Cytokine production. Dendritic cells (DC), antigen-presenting cells (APC) and macrophages (MPh) were activated for 24 h with lipopolysaccharide (LPS, 100 ng/ml). Levels of interleukin (IL)-10 and IL12p70 were determined by specific sandwich ELISA. The mean (SEM) production of six independent experiments is shown. (B) Phagocytic activity. Uptake of FITC-dextran by DC, APC and MPh after 1 h was assessed by flow cytometry. Data are shown as the mean (SEM) of at least three independent experiments. Different epithelial cell donors and blood donors were used in each experiment. *p<0.05 (t test).