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. 2009 Mar;126(3):316–328. doi: 10.1111/j.1365-2567.2008.03050.x

Figure 4.

Figure 4

Partial epigenetic map of the mouse Aicda locus (35, 400 bps) in lipopolysaccharide + interleukin-4 activated B cells depicting polymerase II binding, messenger RNA (mRNA) production, histone H3 and H4 acetylation, and histone H3 lysine 4 mono-, di-, or tri-methylation (H3K4me1-2-3). Phylogenetically conserved elements CNSVIII, activation-induced cytidine deiminase (AID) basal promoter (BP), AID intronic enhancer (AIDE), and CNSX are also highlighted. Mapping (200 base pair resolution) was produced by Solexa DNA microsequencing of immunoprecipitated chromatin (PolII, H3Ac, H4Ac, H3K4me1-2-3) or polyA+ isolated mRNA (Yamane and Casellas, manuscript in preparation).