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. 1989 Oct;27(10):2226–2229. doi: 10.1128/jcm.27.10.2226-2229.1989

Cerebral phaeohyphomycosis caused by Chaetomium globosum in a renal transplant recipient.

V Anandi 1, T J John 1, A Walter 1, J C Shastry 1, M K Lalitha 1, A A Padhye 1, L Ajello 1, F W Chandler 1
PMCID: PMC266999  PMID: 2584374

Abstract

A 32-year-old male patient developed headaches, vomiting, blurring of vision, and focal seizures of the left side of the face 2 months after a renal transplant. He developed a brain abscess and died. Direct KOH examination of the brain tissue demonstrated hyaline as well as dematiaceous, septate hyphae. Histologic examination of brain sections revealed polymorphous fungal elements consisting of septate, dark-pigmented hyphae, intercalary and terminal swollen fungal cells, and budding yeastlike cells characteristic of phaeohyphomycosis. Chaetomium globosum was isolated from the brain tissue on all of the fungal media used. This case represents the first histologically and culturally documented phaeohyphomycotic brain infection caused by C. globosum.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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