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Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1989 Dec;27(12):2834–2837. doi: 10.1128/jcm.27.12.2834-2837.1989

Comparative evaluation of three products for the detection of Borrelia burgdorferi antibody in human serum.

R D Fister 1, L A Weymouth 1, J C McLaughlin 1, R W Ryan 1, R C Tilton 1
PMCID: PMC267136  PMID: 2687323

Abstract

Eighty human serum specimens tested concomitantly by immunoblot and an enzyme-linked immunosorbent assay developed jointly at the University of Connecticut School of Medicine and the Connecticut Agricultural Experiment Station were used to evaluate three commercially available diagnostic products for Lyme borreliosis. The sources of the kits were Hillcrest Biologicals, Cypress, Calif.; Whittaker Bioproducts, Walkersville, Md.; and Cambridge Bioscience, Worcester, Mass. When compared with Western blot analysis, the sensitivities and specificities, respectively, for the diagnostic assays were as follows: Hillcrest Biologicals, 93 and 75%; Whittaker Bioproducts, 73 and 100%; Cambridge Bioscience, 89 and 100%; and University of Connecticut School of Medicine, 96 and 92%.

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Selected References

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