Abstract
The sensitivity of the mouse antibody production test with intraperitoneal or intrasplenic inoculation of mice with reovirus type 3, minute virus of mice, lymphocytic choriomeningitis virus, or mouse hepatitis virus was compared with that of direct isolation in cultured cells. The mouse antibody production test for detection of mouse hepatitis virus was significantly more sensitive than virus isolation in permissive cells, but differences in sensitivity were less marked for the other three viruses. The intrasplenic route of inoculation did not yield seroconversion that occurred earlier or more consistently than that detected after intraperitoneal inoculation.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bhatt P. N., Jacoby R. O., Barthold S. W. Contamination of transplantable murine tumors with lymphocytic choriomeningitis virus. Lab Anim Sci. 1986 Apr;36(2):136–139. [PubMed] [Google Scholar]
- Carthew P. Is rodent virus contamination of monoclonal antibody preparations for use in human therapy a hazard? J Gen Virol. 1986 Jun;67(Pt 6):963–974. doi: 10.1099/0022-1317-67-6-963. [DOI] [PubMed] [Google Scholar]
- Collins M. J., Jr, Parker J. C. Murine virus contaminants of leukemia viruses and transplantable tumors. J Natl Cancer Inst. 1972 Oct;49(4):1139–1143. [PubMed] [Google Scholar]
- Gregg M. B. Recent outbreaks of lymphocytic choriomeningitis in the United States of America. Bull World Health Organ. 1975;52(4-6):549–553. [PMC free article] [PubMed] [Google Scholar]
- Kawamata J., Yamanouchi T., Dohmae K., Miyamoto H., Takahaski M., Yamanishi K., Kurata T., Lee H. W. Control of laboratory acquired hemorrhagic fever with renal syndrome (HFRS) in Japan. Lab Anim Sci. 1987 Aug;37(4):431–436. [PubMed] [Google Scholar]
- Makino S., Taguchi F., Fujiwara K. Defective interfering particles of mouse hepatitis virus. Virology. 1984 Feb;133(1):9–17. doi: 10.1016/0042-6822(84)90420-3. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Pike R. M. Laboratory-associated infections: incidence, fatalities, causes, and prevention. Annu Rev Microbiol. 1979;33:41–66. doi: 10.1146/annurev.mi.33.100179.000353. [DOI] [PubMed] [Google Scholar]
- ROWE W. P., HARTLEY J. W., ESTES J. D., HUEBNER R. J. Studies of mouse polyoma virus infection. 1. Procedures for quantitation and detection of virus. J Exp Med. 1959 Apr 1;109(4):379–391. doi: 10.1084/jem.109.4.379. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Smith A. L. An immunofluorescence test for detection of serum antibody to rodent coronaviruses. Lab Anim Sci. 1983 Apr;33(2):157–160. [PubMed] [Google Scholar]
- Smith A. L., Paturzo F. X., Gardner E. P., Morgenstern S., Cameron G., Wadley H. Two epizootics of lymphocytic choriomeningitis virus occurring in laboratory mice despite intensive monitoring programs. Can J Comp Med. 1984 Jul;48(3):335–337. [PMC free article] [PubMed] [Google Scholar]
- Smith A. L. Response of weanling random-bred mice to inoculation with minute virus of mice. Lab Anim Sci. 1983 Feb;33(1):37–39. [PubMed] [Google Scholar]
- Spitz M., Spitz L., Thorpe R., Eugui E. Intrasplenic primary immunization for the production of monoclonal antibodies. J Immunol Methods. 1984 May 11;70(1):39–43. doi: 10.1016/0022-1759(84)90387-9. [DOI] [PubMed] [Google Scholar]
- Yamanishi K., Dantas J. R., Takahashi M., Yamanouchi T., Domae K., Kawamata J., Kurata T. Isolation of hemorrhagic fever with renal syndrome (HFRS) virus from a tumor specimen in a rat. Biken J. 1983 Dec;26(4):155–160. [PubMed] [Google Scholar]