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. 1989 Mar;27(3):561–563. doi: 10.1128/jcm.27.3.561-563.1989

Characterization of virulence marker antigen of Shigella spp. and enteroinvasive Escherichia coli.

T Pál 1, S B Formal 1, T L Hale 1
PMCID: PMC267358  PMID: 2654184

Abstract

Antisera produced in rabbits immunized with an enteroinvasive O143 strain of Escherichia coli were absorbed with an avirulent derivative of the same strain. The resulting sera have been previously shown to recognize enteroinvasive pathogens when used in an enzyme-linked immunosorbent assay. In the current study, Western blots (immunoblots) showed that such an absorbed rabbit antiserum recognized two proteins (IpaB and IpaC) which are encoded by a large, virulence-associated plasmid. These proteins are the apparent constituents of the virulence marker antigen which is expressed by shigellae and enteroinvasive E. coli.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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