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. 1989 Mar;27(3):568–570. doi: 10.1128/jcm.27.3.568-570.1989

Synthesis and secretion of phospholipase C by oral spirochetes.

R Siboo 1, W al-Joburi 1, M Gornitsky 1, E C Chan 1
PMCID: PMC267363  PMID: 2715327

Abstract

Four strains of oral treponemes and Treponema phagedenis Reiter synthesize and secrete phospholipase C (PLC), which was detected by the hydrolysis of p-nitrophenylphosphorylcholine. PLC was detected in gingival crevicular fluid from diseased but not from healthy sulci. The initiation and progression of periodontal lesions may begin with the hydrolysis of membrane phospholipids by PLC.

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Selected References

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