Table 2.
Ratio of pups obtained from Wnt7a and Vangl2Lp crosses
| Number of mice | Progeny | WT; WT | Vangl2Lp/+ | Wnt7+/− | Wnt7−/− | Vangl2Lp/+; Wnt7−/− | Vangl2Lp/+; Wnt7+/− |
|---|---|---|---|---|---|---|---|
| 53 | Female | 16 | 0 | 22 | 6 | 3 | 6 |
| 38 | Male | 7 | 0 | 12 | 3 | 0 | 16 |
| 91 | Total | 23 | 0 | 34 | 9 | 3 | 22 |
| %Female | 30.2 | 0.0 | 41.5 | 11.3 | 5.7 | 11.3 | |
| %Male | 18.4 | 0.0 | 31.6 | 7.9 | 0.0 | 42.1 | |
| %Total | 25.3 | 0.0 | 37.4 | 9.9 | 3.3 | 24.2 | |
| %Expected | 12.5 | 12.5 | 25.0 | 12.5 | 12.5 | 25.0 | |
| %Difference | −12.8 | 12.5 | −12.4 | 2.6 | 9.2 | 0.8 |
Wnt7a+/− females were crossed to Wnt7a+/−; Vangl2Lp/+ double heterozygotes. Expected Mendelian ratios are given in the penultimate row. ϰ2<0.01.
Lp, the Vangl2Lp mutation; WT, wild type; Wnt7 is Wnt7a.