TABLE 4.
Linkage disequilibrium variance components within and among time point samples within patients
|
N
|
Mean
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Patient ID | Samples | Yr | Sequences | Site pairs |  |
 |
 |
 |
 |
| 10149483 | 2 | 1 | 154 | 0 | — | — | — | — | — |
| 10149484 | 2 | 1 | 158 | 4 | 0.02712 | 0.13702 | 0.15073 | 0.02765 | 0.17838 |
| 10149482 | 3 | 4 | 306 | 3 | 0.04680 | 0.09851 | 0.11768 | 0.04139 | 0.15907 |
| 10160923** | 2 | 4 | 105 | 29 | 0.00841 | 0.55047 | 0.39583 | 0.17540 | 0.57123 |
| 10160924 | 2 | 4 | 113 | 0 | — | — | — | — | — |
The numbers of samples, of years between first and last samples, of total sequences sampled, and of site pairs with statistically significant linkage disequilibrium are shown (N). Variance components are means across site pairs. **dN (SE) = 0.1648 (0.0349); dS (SE) = 0.0055 (0.0021); H0, dN = dS; Z = 3.21; P < 0.01.