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. 2009 May;182(1):411.

CORRIGENDUM

PMCID: PMC2674840

In the article by L. E. Bauman, J. S. Sinsheimer, E. M. Sobel and K. Lange (Genetics 180: 1743–1761) entitled “Mixed Effects Models for Quantitative Trait Loci Mapping With Inbred Strains,” recurrence (7) describing the calculation of the strain coefficient matrix for an individual with itself should read

graphic file with name M1.gif

where diag(γ) denotes a diagonal matrix whose diagonal entries coincide with the entries of the vector γ and k and l are the parents of i.

In appendix b, recurrence (B3) should read

graphic file with name M2.gif

Proposition 1e should read

Proposition 1. In addition to satisfying the recurrences (B1), (B2), and (B3), the matrix Cij

e. has entries Cij(m, n) confined to the interval Inline graphic for nm and to the interval Inline graphic for n = m.

In the next paragraph, the constant aij for s = 2 strains should satisfy Inline graphic. Furthermore, for the assertion since αij = 0 whenever i or j is a founder or an F1 individual, straightforward recursive arguments show that within any strictly linear mating designs like Fn, αij = 0 for all ij is not true.

Finally, in Proposition 2 the bound on the coefficients aij,mn is slightly changed. The coefficients aij,mn are nonnegative dyadic rationals satisfying

graphic file with name M6.gif

The proofs for Proposition 1e and for Proposition 2 remain essentially the same, as do all numerical examples.


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