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. 1989 Aug;27(8):1893–1895. doi: 10.1128/jcm.27.8.1893-1895.1989

Sensitivity and specificity of pooled versus individual sera in a human immunodeficiency virus antibody prevalence study.

B Cahoon-Young 1, A Chandler 1, T Livermore 1, J Gaudino 1, R Benjamin 1
PMCID: PMC267694  PMID: 2504779

Abstract

We evaluated the efficacy of testing pooled versus individual sera for the detection of human immunodeficiency virus antibody. A total of 5,000 individual specimens and 500 pools of 10 specimens each were assayed by an enzyme-linked immunosorbent assay. There was complete agreement in human immunodeficiency virus enzyme-linked immunosorbent assay reactivity for pooled versus individual specimens. An estimated savings of 60 to 80% (labor and supplies) can be realized dependent upon pooling and assay format.

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Selected References

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