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Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1990 Jun;28(6):1194–1197. doi: 10.1128/jcm.28.6.1194-1197.1990

Immunodominant epitopes of the adhesin of Mycoplasma pneumoniae.

E Jacobs 1, A Pilatschek 1, B Gerstenecker 1, K Oberle 1, W Bredt 1
PMCID: PMC267904  PMID: 1696281

Abstract

Overlapping octapeptides from the amino acid sequence of the adherence protein of Mycoplasma pneumoniae were synthesized and used as the antigen in an enzyme-linked immunosorbent assay with serum samples from M. pneumoniae-infected patients. Of a sequence of 338 amino acids positioned between leucine 801 and leucine 1139, only two regions with immunodominant continuous epitopes were detected. The immunoglobulin G and immunoglobulin M antibodies of child and adult patients reacted especially with the NH2-(810)-W-I-G-N-G-Y-R-Y peptide but also reacted with the NH2-(1124)-F-T-D-F-V-K-P-R peptide.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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