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. 1990 Jul;28(7):1673–1675. doi: 10.1128/jcm.28.7.1673-1675.1990

The 83-kilodalton antigen of Borrelia burgdorferi which stimulates immunoglobulin M (IgM) and IgG responses in infected hosts is expressed by a chromosomal gene.

R B Lefebvre 1, G C Perng 1, R C Johnson 1
PMCID: PMC268016  PMID: 2380391

Abstract

We report the cloning and characterization of a chromosomal gene from Borrelia burgdorferi expressing an 83-kilodalton protein antigen in Escherichia coli. The antigen reacted strongly with antisera from two human Lyme disease patients. The chromosomal gene was expressed in a 6.5-kilobase-pair ClaI fragment cloned into a variable-reading-frame plasmid vector.

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Selected References

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