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. 1990 Sep;28(9):1881–1886. doi: 10.1128/jcm.28.9.1881-1886.1990

Comparison of epidemic and endemic group G streptococci by restriction enzyme analysis.

N J Martin 1, E L Kaplan 1, M A Gerber 1, M A Menegus 1, M Randolph 1, K Bell 1, P P Cleary 1
PMCID: PMC268071  PMID: 2172291

Abstract

Restriction enzyme profiles of group G beta-hemolytic streptococci associated with a point source outbreak and an outbreak of sporadic pharyngitis in two different communities were compared. To asses the epidemiologic utility of this approach for studying group G streptococci, DNA fingerprints of strains responsible for a point source outbreak of pharyngitis associated with the consumption of contaminated food were compared with DNA fingerprints of pharyngeal isolates from children with pharyngitis seen at a pediatric practice during a 6-month period. In each epidemiologic situation, a single strain characterized by a unique restriction enzyme pattern predominated. The results are compatible with the conclusion that human infections could be limited to a few strains of group G streptococci which have the capacity to spread through a given population. The restriction enzyme profiles proved to be a highly specific and precise means of evaluating strain relatedness and of providing further understanding of the epidemiology of group G streptococcal infections.

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Selected References

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