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Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1990 Dec;28(12):2621–2626. doi: 10.1128/jcm.28.12.2621-2626.1990

Coaggregation of oral Candida isolates with bacteria from bone marrow transplant recipients.

L Y Hsu 1, G E Minah 1, D E Peterson 1, J R Wingard 1, W G Merz 1, V Altomonte 1, C A Tylenda 1
PMCID: PMC268245  PMID: 2279992

Abstract

In vitro coaggregation between Candida species isolated from immunosuppressed bone marrow transplant recipients and oral bacteria was investigated. Each Candida strain showed a different pattern of coaggregation with the 22 bacterial strains studied. Two strains of Lactobacillus amylovorus isolated from separate bone marrow transplant patients and Fusobacterium nucleatum (VPI 10197) coaggregated with all Candida strains. Ten bacterial strains showed no coaggregation with the Candida strains. A variety of inhibition patterns were observed when coaggregating strains were first incubated with various sugars or subjected to heat treatment. Positive and negative results were generally consistent with all Candida strains. On the basis of the culture characteristics of the oral rinse specimens, relationships between the colonization of bacteria and yeasts and in vitro coaggregation were suggested.

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Selected References

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  1. Allen C. M., Beck F. M. Differences in mucosal reaction related to Candida albicans isolates. J Oral Pathol. 1987 Feb;16(2):89–93. doi: 10.1111/j.1600-0714.1987.tb00693.x. [DOI] [PubMed] [Google Scholar]
  2. Bagg J., Silverwood R. W. Coagglutination reactions between Candida albicans and oral bacteria. J Med Microbiol. 1986 Sep;22(2):165–169. doi: 10.1099/00222615-22-2-165. [DOI] [PubMed] [Google Scholar]
  3. Brawner D. L., Cutler J. E. Oral Candida albicans isolates from nonhospitalized normal carriers, immunocompetent hospitalized patients, and immunocompromised patients with or without acquired immunodeficiency syndrome. J Clin Microbiol. 1989 Jun;27(6):1335–1341. doi: 10.1128/jcm.27.6.1335-1341.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Chaffin W. L., Skudlarek J., Morrow K. J. Variable expression of a surface determinant during proliferation of Candida albicans. Infect Immun. 1988 Feb;56(2):302–309. doi: 10.1128/iai.56.2.302-309.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Critchley I. A., Douglas L. J. Role of glycosides as epithelial cell receptors for Candida albicans. J Gen Microbiol. 1987 Mar;133(3):637–643. doi: 10.1099/00221287-133-3-637. [DOI] [PubMed] [Google Scholar]
  6. Eke P. I., Rotimi V. O., Laughon B. E. Coaggregation of black-pigmented Bacteroides species with other oral bacteria. J Med Microbiol. 1989 Jan;28(1):1–4. doi: 10.1099/00222615-28-1-1. [DOI] [PubMed] [Google Scholar]
  7. Eshdat Y., Ofek I., Yashouv-Gan Y., Sharon N., Mirelman D. Isolation of a mannose-specific lectin from Escherichia coli and its role in the adherence of the bacteria to epithelial cells. Biochem Biophys Res Commun. 1978 Dec 29;85(4):1551–1559. doi: 10.1016/0006-291x(78)91179-8. [DOI] [PubMed] [Google Scholar]
  8. Falkler W. A., Jr, Hawley C. E. Hemagglutinating activity of Fusobacterium nucleatum. Infect Immun. 1977 Jan;15(1):230–238. doi: 10.1128/iai.15.1.230-238.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Gibbons R. J., van Houte J. Selective bacterial adherence to oral epithelial surfaces and its role as an ecological determinant. Infect Immun. 1971 Apr;3(4):567–573. doi: 10.1128/iai.3.4.567-573.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Gold O. G., Jordan H. V., Van Houte J. A selective medium for Streptococcus mutans. Arch Oral Biol. 1973 Nov;18(11):1357–1364. doi: 10.1016/0003-9969(73)90109-x. [DOI] [PubMed] [Google Scholar]
  11. Howlett J. A., Squier C. A. Candida albicans ultrastructure: colonization and invasion of oral epithelium. Infect Immun. 1980 Jul;29(1):252–260. doi: 10.1128/iai.29.1.252-260.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Jenkinson H. F., Lala H. C., Shepherd M. G. Coaggregation of Streptococcus sanguis and other streptococci with Candida albicans. Infect Immun. 1990 May;58(5):1429–1436. doi: 10.1128/iai.58.5.1429-1436.1990. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Kelstrup J. The incidence of bacteroides melaniogenicus in human gingival sulci, and its prevalence in the oral cavity at different ages. Periodontics. 1966 Jan-Feb;4(1):14–18. [PubMed] [Google Scholar]
  14. Liljemark W. F., Gibbons R. J. Proportional distribution and relative adherence of Streptococcus miteor (mitis) on various surfaces in the human oral cavity. Infect Immun. 1972 Nov;6(5):852–859. doi: 10.1128/iai.6.5.852-859.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Loesche W. J., Hockett R. N., Syed S. A. The predominant cultivable flora of tooth surface plaque removed from institutionalized subjects. Arch Oral Biol. 1972 Sep;17(9):1311–1325. doi: 10.1016/0003-9969(72)90164-1. [DOI] [PubMed] [Google Scholar]
  16. Macura A. B. Hydrophobicity of Candida albicans related to their adherence to mucosal epithelial cells. Zentralbl Bakteriol Mikrobiol Hyg A. 1987 Oct;266(3-4):491–496. doi: 10.1016/s0176-6724(87)80231-6. [DOI] [PubMed] [Google Scholar]
  17. McCourtie J., Douglas L. J. Relationship between cell surface composition, adherence, and virulence of Candida albicans. Infect Immun. 1984 Jul;45(1):6–12. doi: 10.1128/iai.45.1.6-12.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Meyers J. D., Atkinson K. Infection in bone marrow transplantation. Clin Haematol. 1983 Oct;12(3):791–811. doi: 10.1016/s0308-2261(83)80011-3. [DOI] [PubMed] [Google Scholar]
  19. Meyers J. D. Infection in bone marrow transplant recipients. Am J Med. 1986 Jul 28;81(1A):27–38. doi: 10.1016/0002-9343(86)90511-5. [DOI] [PubMed] [Google Scholar]
  20. Minah G. E., Rednor J. L., Peterson D. E., Overholser C. D., Depaola L. G., Suzuki J. B. Oral succession of gram-negative bacilli in myelosuppressed cancer patients. J Clin Microbiol. 1986 Aug;24(2):210–213. doi: 10.1128/jcm.24.2.210-213.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Minah G. E., Solomon E. S., Chu K. The association between dietary sucrose consumption and microbial population shifts at six oral sites in man. Arch Oral Biol. 1985;30(5):397–401. doi: 10.1016/0003-9969(85)90066-4. [DOI] [PubMed] [Google Scholar]
  22. Mirelman D., Altmann G., Eshdat Y. Screening of bacterial isolates for mannose-specific lectin activity by agglutination of yeasts. J Clin Microbiol. 1980 Apr;11(4):328–331. doi: 10.1128/jcm.11.4.328-331.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Mongiello J. R., Falkler W. A., Jr Sugar inhibition of oral Fusobacterium nucleatum haemagglutination and cell binding. Arch Oral Biol. 1979;24(7):539–545. doi: 10.1016/0003-9969(79)90133-x. [DOI] [PubMed] [Google Scholar]
  24. Peterson D. E., Minah G. E., Overholser C. D., Suzuki J. B., DePaola L. G., Stansbury D. M., Williams L. T., Schimpff S. C. Microbiology of acute periodontal infection in myelosuppressed cancer patients. J Clin Oncol. 1987 Sep;5(9):1461–1468. doi: 10.1200/JCO.1987.5.9.1461. [DOI] [PubMed] [Google Scholar]
  25. Sandford G. R., Merz W. G., Wingard J. R., Charache P., Saral R. The value of fungal surveillance cultures as predictors of systemic fungal infections. J Infect Dis. 1980 Oct;142(4):503–509. doi: 10.1093/infdis/142.4.503. [DOI] [PubMed] [Google Scholar]
  26. Theilade E., Wright W. H., Jensen S. B., Löe H. Experimental gingivitis in man. II. A longitudinal clinical and bacteriological investigation. J Periodontal Res. 1966;1:1–13. doi: 10.1111/j.1600-0765.1966.tb01842.x. [DOI] [PubMed] [Google Scholar]
  27. Tronchin G., Poulain D., Herbaut J., Biguet J. Localization of chitin in the cell wall of Candida albicans by means of wheat germ agglutinin. Fluorescence and ultrastructural studies. Eur J Cell Biol. 1981 Dec;26(1):121–128. [PubMed] [Google Scholar]
  28. Walker C. B., Ratliff D., Muller D., Mandell R., Socransky S. S. Medium for selective isolation of Fusobacterium nucleatum from human periodontal pockets. J Clin Microbiol. 1979 Dec;10(6):844–849. doi: 10.1128/jcm.10.6.844-849.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. Zylber L. J., Jordan H. V. Development of a selective medium for detection and enumeration of Actinomyces viscosus and Actinomyces naeslundii in dental plaque. J Clin Microbiol. 1982 Feb;15(2):253–259. doi: 10.1128/jcm.15.2.253-259.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]

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