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. 1985 Sep;22(3):462–464. doi: 10.1128/jcm.22.3.462-464.1985

Examination of the Rotazyme II enzyme immunoassay for the diagnosis of rotavirus gastroenteritis.

M Chernesky, S Castriciano, J Mahony, D DeLong
PMCID: PMC268437  PMID: 2995441

Abstract

Rotazyme II, which is a shorter version of Rotazyme (less than 3 h), was compared with electron microscopy and Rotazyme for sensitivity and specificity on 229 human stool specimens. Compared with electron microscopy, the newer assay was found to be 99.4% sensitive and 97.3% specific for an overall agreement of 98.7%. After resolution of discordant results by blocking tests, the Rotazyme II enzyme immunoassay was shown to be more sensitive than electron microscopy and, therefore, 100% specific.

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Selected References

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