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Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1985 Nov;22(5):877–879. doi: 10.1128/jcm.22.5.877-879.1985

Comparison of polyclonal antiserum versus monoclonal antibodies for the rapid diagnosis of influenza A virus infections by immunofluorescence in clinical specimens.

I Shalit, P A McKee, H Beauchamp, J L Waner
PMCID: PMC268551  PMID: 3902885

Abstract

A pool of monoclonal antibodies was compared with polyclonal antiserum for the rapid detection of influenza A virus in 28 clinical specimens by immunofluorescence. Monoclonal antibodies showed higher sensitivity (69 versus 46%) and accuracy (86 versus 75%) and easier slide interpretation than did polyclonal antiserum. The procedure proved useful for rapid detection of a community outbreak of influenza A virus infection.

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Selected References

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