Table 2.

Experimental and predicted melting temperatures for the set of RNA pairs reported in Diamond et al. (2001)

Pairs	Experiment		piRNA		RNAcofold		UNAFold
	Tl	Tc
A	28.7	30.3	32.44		50.99		21.52
B	19	20.5	31.55		52.55		33.22
C	33.6	33.6	32.94		53.11		39.77
D	33.9	36	32.43		51.02		26.85
E	23	24.4	31.66		52.48		32.22
F	34.9	36.9	33.28		54.7		39.91
G	32.4	33.6	32.76		49.76		64.27
H	16.1	18.9	36.41		57.92		29.76
I	29	32.3	32.32		50.99		29.18
J	32.3	37.1	37.01		56.92		28.8
K	23.4	30.7	31.45		49.36		26.18
L	33.5	35.4	32.61		50.51		28.01
		Tl	Tl	Tc	Tl	Tc	Tl	Tc
Avg. difference		2.49	5.53	4.19	24.21	21.72	8.86	9.38
Spearman rank corr.		0.87	0.36	0.45	−0.05	0	0.16	0.03

Each pair is referred to by an identifier (A, B,…, L). Please refer to our Supplementary Material or Diamond et al. (2001) to see the exact sequences of each pair. All values, except Spearman's rank correlation, are in degree centigrade. Bold entries are the most accurate predictions. In other words, they have the least difference from experimental measurements.