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. 1986 Jun;23(6):1152–1154. doi: 10.1128/jcm.23.6.1152-1154.1986

Surveillance of mice for antibodies to murine cytomegalovirus.

C A Anderson, J C Murphy, J G Fox
PMCID: PMC268815  PMID: 3011855

Abstract

The sera of 256 mice from nine commercial sources were screened for antibodies to murine cytomegalovirus (MCMV) because a surveillance of this virus has not been reported in the literature for over a decade. Although no evidence of antibodies to MCMV were detected by complement fixation or nuclear anticomplement immunofluorescence, 54.7% of these sera did have antibodies that were detected by enzyme-linked immunosorbent assay. These data emphasize the need for proper containment of laboratory mice to prevent the potential outbreak of acute MCMV infection. Including MCMV antibody surveillance by enzyme-linked immunosorbent assay in routine health monitoring of mice and imparting these findings in an analysis of the role of MCMV on interpretation of experimental results is advised.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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