Skip to main content
Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1986 Sep;24(3):448–450. doi: 10.1128/jcm.24.3.448-450.1986

Tentative disk diffusion susceptibility interpretive criteria for pefloxacin.

P C Fuchs, A L Barry, R N Jones, C Thornsberry
PMCID: PMC268932  PMID: 3463566

Abstract

Standardized broth microdilution and disk diffusion susceptibility tests for pefloxacin were performed on 585 clinical isolates. The 5-micrograms pefloxacin disk is recommended, and the following breakpoints are proposed: susceptible, greater than or equal to 19 mm (MIC, less than or equal to 2.0 micrograms/ml); resistant, less than or equal to 15 mm (MIC, greater than 4.0 micrograms/ml); and intermediate, 16 to 18 mm.

Full text

PDF
448

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Clarke A. M., Zemcov S. J., Campbell M. E. In-vitro activity of pefloxacin compared to enoxacin, norfloxacin, gentamicin and new beta-lactams. J Antimicrob Chemother. 1985 Jan;15(1):39–44. doi: 10.1093/jac/15.1.39. [DOI] [PubMed] [Google Scholar]
  2. Jones R. N., Barry A. L. Norfloxacin (MK-0366, AM-715): in vitro activity and cross-resistance with other organic acids including quality control limits for disk diffusion testing. Diagn Microbiol Infect Dis. 1983 Jun;1(2):165–172. doi: 10.1016/0732-8893(83)90047-0. [DOI] [PubMed] [Google Scholar]
  3. Ligtvoet E. E., Wickerhoff-Minoggio T. In-vitro activity of pefloxacin compared with six other quinolones. J Antimicrob Chemother. 1985 Oct;16(4):485–490. doi: 10.1093/jac/16.4.485. [DOI] [PubMed] [Google Scholar]
  4. Montay G., Goueffon Y., Roquet F. Absorption, distribution, metabolic fate, and elimination of pefloxacin mesylate in mice, rats, dogs, monkeys, and humans. Antimicrob Agents Chemother. 1984 Apr;25(4):463–472. doi: 10.1128/aac.25.4.463. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Wolff M., Regnier B., Daldoss C., Nkam M., Vachon F. Penetration of pefloxacin into cerebrospinal fluid of patients with meningitis. Antimicrob Agents Chemother. 1984 Sep;26(3):289–291. doi: 10.1128/aac.26.3.289. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Clinical Microbiology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES