Abstract
Treatment of nasopharyngeal specimens with 0.25% N-acetylcysteine for 20 min at room temperature effectively reduced the nonspecific fluorescence encountered during direct examination of the specimens by immunofluorescence. The treatment did not affect specific antigen staining or the viability of several common respiratory viruses.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Hurst G. A., Shaw P. B., LeMaistre C. A. Laboratory and clinical evaluation of the mucolytic properties of acetylcysteine. Am Rev Respir Dis. 1967 Nov;96(5):962–970. doi: 10.1164/arrd.1967.96.5.962. [DOI] [PubMed] [Google Scholar]
- KUBICA G. P., DYE W. E., COHN M. L., MIDDLEBROOK G. Sputum digestion and decontamination with N-acetyl-L-cysteine-sodium hydroxide for culture of mycobacteria. Am Rev Respir Dis. 1963 May;87:775–779. doi: 10.1164/arrd.1963.87.5.775. [DOI] [PubMed] [Google Scholar]
- LIMBER C. R., REISER H. G., ROETTIG L. C., CURTIS G. M. Enzymatic lysis of respiratory secretions by aerosol trypsin. J Am Med Assoc. 1952 Jun 28;149(9):816–821. doi: 10.1001/jama.1952.02930260018006. [DOI] [PubMed] [Google Scholar]
- SHEFFNER A. L. The reduction in vitro in viscosity of mucoprotein solutions by a new mucolytic agent, N-acetyl-L-cysteine. Ann N Y Acad Sci. 1963 Mar 30;106:298–310. doi: 10.1111/j.1749-6632.1963.tb16647.x. [DOI] [PubMed] [Google Scholar]
- Shah R. R., Dye W. E. Use of dithiothreitol to replace n-acetyl-L-cysteine for routine sputum digestion-decontamination for the culture of mycobacteria. Am Rev Respir Dis. 1966 Sep;94(3):454–454. doi: 10.1164/arrd.1966.94.3.454. [DOI] [PubMed] [Google Scholar]