Abstract
The biochemical characteristics and the presence of human Fc(gamma) receptors of 52 throat isolates of group C beta-hemolytic streptococci were examined. Among these isolates, 38 were identified as "Streptococcus milleri" and 14 were identified as "Streptococcus equisimilis." The differentiation of group C "S. equisimilis" from "S. milleri" with identical group antigens was easy to perform by the measurement of the size of the hemolytic zone on a sheep blood agar plate in an anaerobic atmosphere and by biochemical tests (Voges-Proskauer test). A clear-cut criterion for differentiation was noted among these isolates, i.e., the presence of Fc(gamma) receptors. "S. equisimilis," which are generally associated with pharyngitis, possess human Fc(gamma) receptors, while "S. milleri", which are generally isolated from healthy persons, have no such receptors.
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Selected References
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- Appelbaum P. C., Chaurushiya P. S., Jacobs M. R., Duffett A. Evaluation of the rapid strep system for species identification of streptococci. J Clin Microbiol. 1984 May;19(5):588–591. doi: 10.1128/jcm.19.5.588-591.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ball L. C., Parker M. T. The cultural and biochemical characters of Streptococcus milleri strains isolated from human sources. J Hyg (Lond) 1979 Feb;82(1):63–78. doi: 10.1017/s002217240002547x. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Burova L. A., Christensen P., Grubb R., Jonsson A., Samuelsson G., Schalén C., Svensson M. L. Changes in virulence, M protein and IgG Fc receptor activity in a type 12 group A streptococcal strain during mouse passages. Acta Pathol Microbiol Scand B. 1980 Aug;88(4):199–205. doi: 10.1111/j.1699-0463.1980.tb02629.x. [DOI] [PubMed] [Google Scholar]
- Colman G., Williams R. E. The cell walls of streptococci. J Gen Microbiol. 1965 Dec;41(3):375–387. doi: 10.1099/00221287-41-3-375. [DOI] [PubMed] [Google Scholar]
- Facklam R. R. Physiological differentiation of viridans streptococci. J Clin Microbiol. 1977 Feb;5(2):184–201. doi: 10.1128/jcm.5.2.184-201.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Facklam R. R., Rhoden D. L., Smith P. B. Evaluation of the Rapid Strep system for the identification of clinical isolates of Streptococcus species. J Clin Microbiol. 1984 Nov;20(5):894–898. doi: 10.1128/jcm.20.5.894-898.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lawrence J., Yajko D. M., Hadley W. K. Incidence and characterization of beta-hemolytic Streptococcus milleri and differentiation from S. pyogenes (group A), S. equisimilis (group C), and large-colony group G streptococci. J Clin Microbiol. 1985 Nov;22(5):772–777. doi: 10.1128/jcm.22.5.772-777.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lebrun L., Pillot J., Grangeot-Keros L., D'Azambuja S. An indirect immunofluorescence staining procedure for detection of human Fc gamma receptors on streptococci. J Immunol Methods. 1982;48(3):349–358. doi: 10.1016/0022-1759(82)90335-0. [DOI] [PubMed] [Google Scholar]
- Lebrun L., Pillot J., Grangeot-Keros L., Rannou M. T. Detection of human Fc (gamma) receptors on streptococci by indirect immunofluorescence staining: a survey of streptococci freshly isolated from patients. J Clin Microbiol. 1982 Jul;16(1):200–201. doi: 10.1128/jcm.16.1.200-201.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lütticken R., Wendorff U., Lütticken D., Johnson E. A., Wannamaker L. W. Studies on streptococci resembling Streptococcus milleri and on an associated surface-protein antigen. J Med Microbiol. 1978 Nov;11(4):419–431. doi: 10.1099/00222615-11-4-419. [DOI] [PubMed] [Google Scholar]
- Parker M. T., Ball L. C. Streptococci and aerococci associated with systemic infection in man. J Med Microbiol. 1976 Aug;9(3):275–302. doi: 10.1099/00222615-9-3-275. [DOI] [PubMed] [Google Scholar]
- Ruoff K. L., Kunz L. J., Ferraro M. J. Occurrence of Streptococcus milleri among beta-hemolytic streptococci isolated from clinical specimens. J Clin Microbiol. 1985 Aug;22(2):149–151. doi: 10.1128/jcm.22.2.149-151.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ruoff K. L., Kunz L. J. Use of the Rapid STREP system for identification of viridans streptococcal species. J Clin Microbiol. 1983 Nov;18(5):1138–1140. doi: 10.1128/jcm.18.5.1138-1140.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Van der Auwera P. Clinical significance of Streptococcus milleri. Eur J Clin Microbiol. 1985 Aug;4(4):386–390. doi: 10.1007/BF02148688. [DOI] [PubMed] [Google Scholar]