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Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1987 Jul;25(7):1262–1264. doi: 10.1128/jcm.25.7.1262-1264.1987

Serodiagnosis of rabies by dot immunobinding assay.

R L Heberling, S S Kalter, J S Smith, D G Hildebrand
PMCID: PMC269189  PMID: 3301890

Abstract

A dot immunobinding assay that uses inactivated antigen for the detection of rabies viral antibodies was compared with the rapid fluorescent focus inhibition test. Results of testing pre- and postvaccination sera from humans (n = 33) and canines (n = 22) were identical for both tests. Endpoint titers of positive sera also were approximately the same by both methods. When a mouse monoclonal antibody was used, the dot immunobinding assay antigen was shown to possess detectable rabies virus glycoprotein and core antigens.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Heberling R. L., Kalter S. S. Rapid dot-immunobinding assay on nitrocellulose for viral antibodies. J Clin Microbiol. 1986 Jan;23(1):109–113. doi: 10.1128/jcm.23.1.109-113.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Smith J. S., Yager P. A., Baer G. M. A rapid reproducible test for determining rabies neutralizing antibody. Bull World Health Organ. 1973 May;48(5):535–541. [PMC free article] [PubMed] [Google Scholar]

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