Skip to main content
. 2009 May 13;6:44. doi: 10.1186/1742-4690-6-44

Figure 1.

Figure 1

Synergistic inhibition of HIV-1 replication by combinations TFV+FTC, TFV+EFV, FTC+EFV, and TFV+FTC+EFV analyzed by the median-effect analysis. The solid line presents curve fitting of the CI values as a function of fractional effect. The dashed lines represent 95% confidence interval. The line (in red) at CI = 1 represents additivity. (A) TFV+FTC (1:1 IC50 ratio) with an average CI of 0.47; (B) TFV+EFV (1:1 IC50 ratio) with average CI of 0.54; (C) FTC+EFV (1:1 IC50 ratio) with an average CI of 0.62; (D) TFV+FTC+EFV (1:1:1 IC50 ratio) with an average CI of 0.46.