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. Author manuscript; available in PMC: 2009 Jun 9.
Published in final edited form as: Virology. 2007 Oct 24;370(1):1–11. doi: 10.1016/j.virol.2007.08.003

Table 6.

CPE induced by apoptosis-inducing reagents in Vero, Hs888Lu, and HEF cells

Cells Treatment Time of treatment (hours)
3 6 24 48 72 96
Vero DMSO − − − − − −
Actinomycin D − − ++ ++++ +++++ All dead
Camptothecin − − ++ ++ ++++ All dead
Cycloheximide − − −/+ ++ +++ ++++
Dexamethasone − − − − −/+ −/+
Etoposide − − −/+ ++ ++ +++
Cells Treatment Time of treatment (days)
1 2 3 4 5 6
Hs888Lu DMSO − − − − − −
Actinomycin D −/+ ++ ++ +++ ++++ +++++
Camptothecin −/+ + ++ +++ ++++ +++++
Cycloheximide + + ++ +++ ++++ +++++
Dexamethasone − − −/+ + ++ ++
Etoposide −/+ + ++ +++ ++++ +++++
HEF DMSO − − − − − −
Actinomycin D − − − ++ +++ ++++
Camptothecin − − − − + +
Cycloheximide − + ++ ++ +++ +++
Dexamethasone − − − − − −
Etoposide − − − −/+ + +

CPE key: −/+. less than 5 % cell death; +. ~ 10 % cell death; ++. ~ 25 % cell death; +++. ~ 50 % cell death; ++++. ~ 75 % cell death; +++++. ~ 95 % cell death. The experiment was repeated twice. The data presented is from one experiment and is representative of both independent repetitions.