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. 1987 Nov;25(11):2239–2240. doi: 10.1128/jcm.25.11.2239-2240.1987

Serum albumin treatment to eliminate false-positive results with laboratory rodent specimens tested by rotazyme enzyme-linked immunosorbent assay.

M N Jure 1, S S Morse 1, D M Stark 1
PMCID: PMC269455  PMID: 2826539

Abstract

A high proportion of positive results was found in fecal specimens from mice and rats tested by Rotazyme II enzyme-linked immunosorbent assay, but the presence of virus could not be confirmed. Positive specimens and nonautoclaved rodent diet contained a substance that apparently attached nonspecifically to the antibody-coated beads used in the test and reacted directly with the substrate. Pretreatment of the beads with 0.1% bovine serum albumin eliminated this nonspecific activity.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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