Abstract
A new laboratory animal model for experimental cryptosporidiosis is described. Adult immunosuppressed hamsters were infected per os with 0.5 x 10(5) and 1 x 10(5) Cryptosporidium oocysts of calf origin. The mean numbers of oocysts shed per gram of feces per day and the patterns of infection are described. The susceptibility to Cryptosporidium infection, the total number of oocysts shed (a thousand times the infective dose), and the ease of handling in laboratory conditions make hamsters a good animal model for cryptosporidiosis.
Full text
PDF

Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Arrowood M. J., Sterling C. R. Isolation of Cryptosporidium oocysts and sporozoites using discontinuous sucrose and isopycnic Percoll gradients. J Parasitol. 1987 Apr;73(2):314–319. [PubMed] [Google Scholar]
- Brasseur P., Lemeteil D., Ballet J. J. Rat model for human cryptosporidiosis. J Clin Microbiol. 1988 May;26(5):1037–1039. doi: 10.1128/jcm.26.5.1037-1039.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Current W. L. Cryptosporidiosis. J Am Vet Med Assoc. 1985 Dec 15;187(12):1334–1338. [PubMed] [Google Scholar]
- Current W. L., Haynes T. B. Complete development of Cryptosporidium in cell culture. Science. 1984 May 11;224(4649):603–605. doi: 10.1126/science.6710159. [DOI] [PubMed] [Google Scholar]
- Current W. L., Long P. L. Development of human and calf Cryptosporidium in chicken embryos. J Infect Dis. 1983 Dec;148(6):1108–1113. doi: 10.1093/infdis/148.6.1108. [DOI] [PubMed] [Google Scholar]
- Reese N. C., Current W. L., Ernst J. V., Bailey W. S. Cryptosporidiosis of man and calf: a case report and results of experimental infections in mice and rats. Am J Trop Med Hyg. 1982 Mar;31(2):226–229. doi: 10.4269/ajtmh.1982.31.226. [DOI] [PubMed] [Google Scholar]
- Sherwood D., Angus K. W., Snodgrass D. R., Tzipori S. Experimental cryptosporidiosis in laboratory mice. Infect Immun. 1982 Nov;38(2):471–475. doi: 10.1128/iai.38.2.471-475.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Tzipori S. Cryptosporidiosis in perspective. Adv Parasitol. 1988;27:63–129. doi: 10.1016/S0065-308X(08)60353-X. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Tzipori S., Smith M., Halpin C., Angus K. W., Sherwood D., Campbell I. Experimental cryptosporidiosis in calves: clinical manifestations and pathological findings. Vet Rec. 1983 Feb 5;112(6):116–120. doi: 10.1136/vr.112.6.116. [DOI] [PubMed] [Google Scholar]
- Waldman E., Tzipori S., Forsyth J. R. Separation of Cryptosporidium species oocysts from feces by using a percoll discontinuous density gradient. J Clin Microbiol. 1986 Jan;23(1):199–200. doi: 10.1128/jcm.23.1.199-200.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]