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Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1990 Feb;28(2):385–388. doi: 10.1128/jcm.28.2.385-388.1990

Purification and amino-terminal sequence analysis of the complement-fixing and precipitin antigens from Coccidioides immitis.

S Resnick 1, B Zimmer 1, D Pappagianis 1, A Eakin 1, J McKerrow 1
PMCID: PMC269617  PMID: 2312685

Abstract

Two proteins (21 and 48 kilodaltons) purified from endospore-spherule culture filtrates of Coccidioides immitis are identified as precipitin and complement-fixing antigens, respectively. To allow specific structural comparison to antigens identified by other investigators and as a first step to eventual serodiagnostic antigen production by recombinant DNA technology, amino-terminal amino acid sequences were determined for these antigens.

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Selected References

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