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. 2008 May 16;105(20):384. doi: 10.3238/arztebl.2008.0384b

Correspondence (reply): In Reply

Hanns-Wolf Baenkler *
PMCID: PMC2696882  PMID: 19626177

Professor Stichtenoth’s comments are correct; they should be generally accepted. Thus, the widely used term "analgesic intolerance" is wrong. It is particularly important in medicine to use precise definitions, as medicine is often felt to be an art rather than a science.

This is unfortunately not always successful enough during routine work. There are always "exceptional cases", which is why (as pointed out by Professor Stichtenoth) the contraindication is still included as a precaution in the summaries of product characteristics for the coxibs.

As my article was intended to be an overview of the arachidonic acideicosanoid complex, and not just to cover intolerance, I should just add that the special features I described also include proliferation, especially in the gastrointestinal tract.

Acknowledgments

Translated from the original German by Rodney A. Yeates, M.A., Ph.D.

Footnotes

Conflict of interest statement

The author holds the patent for the functional eicosanoid test.


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