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. 1991 Jan;29(1):192–196. doi: 10.1128/jcm.29.1.192-196.1991

Demonstration of a cell wall antigen cross-reacting with cryptococcal polysaccharide in experimental disseminated trichosporonosis.

G P Melcher 1, K D Reed 1, M G Rinaldi 1, J W Lee 1, P A Pizzo 1, T J Walsh 1
PMCID: PMC269727  PMID: 1993757

Abstract

Patients with disseminated infections caused by Trichosporon beigelii have a circulating antigen that cross-reacts with the polysaccharide capsule of Cryptococcus neoformans. We studied the localization of this antigen by immunoelectron microscopy in a rabbit model of experimental disseminated trichosporonosis. Deparaffinized lung sections were examined by using a murine monoclonal anti-cryptococcal polysaccharide antibody and colloidal gold particles coated with goat antibody to murine immunoglobulin G. Antigen that cross-reacted with the monoclonal antibody was observed in the T. beigelii cell wall and in a fibrillar matrix extending from the cell wall.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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