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. 1991 Jan;29(1):200–201. doi: 10.1128/jcm.29.1.200-201.1991

Serological Cross-Reaction between Legionella pneumophila and Citrobacter freundii in Indirect Immunofluorescence and Rapid Microagglutination Tests

J J Gray 1,*, K N Ward 1, R E Warren 1, M Farrington 1
PMCID: PMC269729  PMID: 1993758

Abstract

We describe the first case in which a diagnostic rise in titers of antibody to formalinized Legionella pneumophila serogroup 1 yolk sac antigen was shown to be caused by a cross-reaction between L. pneumophila and another organism, Citrobacter freundii.

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Selected References

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  1. Edelstein P. H., McKinney R. M., Meyer R. D., Edelstein M. A., Krause C. J., Finegold S. M. Immunologic diagnosis of Legionnaires' disease: cross-reactions with anaerobic and microaerophilic organisms and infections caused by them. J Infect Dis. 1980 May;141(5):652–655. doi: 10.1093/infdis/141.5.652. [DOI] [PubMed] [Google Scholar]
  2. Gray J. J., Alvey B., Smith D. J., Wreghitt T. G. Evaluation of a commercial latex agglutination test for detecting antibodies to cytomegalovirus in organ donors and transplant recipients. J Virol Methods. 1987 May;16(1-2):13–19. doi: 10.1016/0166-0934(87)90026-7. [DOI] [PubMed] [Google Scholar]
  3. Harrison T. G., Taylor A. G. A rapid microagglutination test for the diagnosis of Legionella pneumophila (serogroup 1) infection. J Clin Pathol. 1982 Sep;35(9):1028–1031. doi: 10.1136/jcp.35.9.1028. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Klein G. C. Cross-reaction to Legionella pneumophila antigen in sera with elevated titers to Pseudomonas pseudomallei. J Clin Microbiol. 1980 Jan;11(1):27–29. doi: 10.1128/jcm.11.1.27-29.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Lattimer G. L., Ormsbee R. A., Peacock M. G., Rhodes L. V. Diagnostic specificity of immunoglobulin M (IgM) response in differentiation Legionnaires' disease from psittacosis. Scand J Infect Dis. 1979;11(4):271–273. doi: 10.3109/inf.1979.11.issue-4.03. [DOI] [PubMed] [Google Scholar]
  6. Taylor A. G., Harrison T. G. Formalised yolk sac antigen in early diagnosis of Legionnaires' disease caused by Legionella pneumophila serogroup 1. Lancet. 1981 Sep 12;2(8246):591–592. doi: 10.1016/s0140-6736(81)90988-0. [DOI] [PubMed] [Google Scholar]
  7. Tsai T. F., Fraser D. W. The diagnosis of Legionnaires' disease. Ann Intern Med. 1978 Sep;89(3):413–414. doi: 10.7326/0003-4819-89-3-413. [DOI] [PubMed] [Google Scholar]
  8. Wilkinson H. W., Farshy C. E., Fikes B. J., Cruce D. D., Yealy L. P. Measure of immunoglobulin G-, M-, and A-specific titers against Legionella pneumophila and inhibition of titers against nonspecific, gram-negative bacterial antigens in the indirect immunofluorescence test for legionellosis. J Clin Microbiol. 1979 Nov;10(5):685–689. doi: 10.1128/jcm.10.5.685-689.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]

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