Abstract
Almost 100% of 52 cattle tested from the southern areas of Zimbabwe were found to have antibodies reactive with Rickettsia conorii compared with less than 30% of 120 cattle from the north. Steers artificially infected with R. conorii isolated from Amblyomma hebraeum were found to show no hematological or biochemical signs of disease but did seroconvert. Clinical signs of infection were restricted to regional lymphadenopathy and dermal erythema, edema, and tenderness at the inoculation site. Rickettsemia was detectable for at least 32 days postinfection. Our findings indicate that cattle could be involved in the transmission of rickettsias by A. hebraeum and may serve as a reservoir of human tick-bite fever in southern Africa.
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- Burgdorfer W. Hemolymph test. A technique for detection of rickettsiae in ticks. Am J Trop Med Hyg. 1970 Nov;19(6):1010–1014. [PubMed] [Google Scholar]
- Davidson M. G., Breitschwerdt E. B., Walker D. H., Nasisse M. P., Sussman W. E. Identification of rickettsiae in cutaneous biopsy specimens from dogs with experimental Rocky Mountain spotted fever. J Vet Intern Med. 1989 Jan-Mar;3(1):8–11. [PubMed] [Google Scholar]
- GEAR J. The rickettsial diseases of Southern Africa; a review of recent studies. S Afr J Clin Sci. 1954 Sep;5(3):158–175. [PubMed] [Google Scholar]
- GIMENEZ D. F. STAINING RICKETTSIAE IN YOLK-SAC CULTURES. Stain Technol. 1964 May;39:135–140. doi: 10.3109/10520296409061219. [DOI] [PubMed] [Google Scholar]
- Montenegro M. R., Mansueto S., Hegarty B. C., Walker D. H. The histology of "taches noires" of boutonneuse fever and demonstration of Rickettsia conorii in them by immunofluorescence. Virchows Arch A Pathol Anat Histopathol. 1983;400(3):309–317. doi: 10.1007/BF00612192. [DOI] [PubMed] [Google Scholar]
- Ormsbee R., Peacock M., Gerloff R., Tallent G., Wike D. Limits of rickettsial infectivity. Infect Immun. 1978 Jan;19(1):239–245. doi: 10.1128/iai.19.1.239-245.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Philip C. B., Hoogstraal H., Reiss-Gutfreund R., Clifford C. M. Evidence of rickettsial disease agents in ticks from Ethiopian cattle. Bull World Health Organ. 1966;35(2):127–131. [PMC free article] [PubMed] [Google Scholar]
- Philip R. N., Casper E. A., Burgdorfer W., Gerloff R. K., Hughes L. E., Bell E. J. Serologic typing of rickettsiae of the spotted fever group by microimmunofluorescence. J Immunol. 1978 Nov;121(5):1961–1968. [PubMed] [Google Scholar]
- Raoult D., Toga B., Dunan S., Davoust B., Quilici M. Mediterranean spotted fever in the South of France; serosurvey of dogs. Trop Geogr Med. 1985 Sep;37(3):258–260. [PubMed] [Google Scholar]
- Tringali G., Intonazzo V., Perna A. M., Mansueto S., Vitale G., Walker D. H. Epidemiology of boutonneuse fever in western Sicily. Distribution and prevalence of spotted fever group rickettsial infection in dog ticks (Rhipicephalus sanguineus). Am J Epidemiol. 1986 Apr;123(4):721–727. doi: 10.1093/oxfordjournals.aje.a114292. [DOI] [PubMed] [Google Scholar]
- Weiss E., Coolbaugh J. C., Williams J. C. Separation of viable Rickettsia typhi from yolk sac and L cell host components by renografin density gradient centrifugation. Appl Microbiol. 1975 Sep;30(3):456–463. doi: 10.1128/am.30.3.456-463.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]