A NO-releasing derivative of acetaminophen spares the liver by acting at several checkpoints in the Fas pathway by Stefano Fiorucci, Elisabetta Antonelli, Andrea Mencarelli, Barbara Palazzetti, Lorena Alvarez-Miller, Marcelo Muscara, Piero Del Soldato, Laura Sanpaolo, John L Wallace and Antonio Morelli (Br J Pharmacol 135; 589–599; 2002) has been retracted by agreement between Professor A Morelli (Head of Gastroenterology, University of Perugia); other co-authors of the paper E Antonelli, B Palazzetti, MN Muscara, P Del Soldato, JL Wallace; the Editor-in-Chief of the British Journal of Pharmacology and Wiley-Blackwell.
Concerns were raised about the authenticity of PCR gel band images in several papers of Fiorucci et al; and were investigated by an official Committee of Inquiry set up by the University of Perugia. Although the inquiry was unable to draw conclusions regarding this paper because the original records were not available, it is clear to the Editors that part of a gel band in Figure 4 has been blacked out, without any comment in the text or legend, so this paper is being retracted based upon the Journal's own expert opinion.
doi: 10.1111/j.1476-5381.2009.00272.x