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. 2009 Mar 22;95(14):1165–1171. doi: 10.1136/hrt.2008.160465

Table 1. Patient data and CRT effects according to diagnostic group.

Patient data All (n = 109) CHD (CRT only) (n = 71) CHD (CRT + concurrent cardiac surgery) (n = 16) Congenital AV block (n = 12) DCMP (n = 10) p Value*
Age at CRT (years), median 16.9 25.5 13.9 3.6 12.7 <0.001
Follow-up on CRT (months), median 7.5 8.8 4.0 9.5 2.3 0.099
Initial QRS (ms), median 160 160 160 155 144 0.082
Initial SVEDD (z score), median 3.3 2.5 2.6 3.7 5.5 0.131
Initial EF/FAC (%), median 27.0 27.5 24.5 24.5 22.0 0.602
Initial SAVV regurgitation (grade), median 1 1 0 1 2 0.589
Initial NYHA class (median) 2.5 2.5 2.0 2.5 4.0 0.058
Change in QRS (ms), median −40§ −40§ −46§ −40§ −15 0.268
Change in SVEDD (z score), median −1.1§ −1.2§ −0.8 −2.2¶ −0.4 0.582
Change in EF/FAC (%), mean (SD) +11.5 (14.3)§ +9.9 (13.8)§ +12.3 (17.1)¶ +23.5 (12.2)¶ +10.8 (11.9)% 0.358
Change in SAVV regurgitation (grade), median −1§ 0 0 −1¶ 0 0.556
Change in NYHA class (median) −1.0§ −1.0§ −1.0† −1.0‡ 0.0 0.028
Non-responders 15/94 7/60 0/13 2/12 6/9 <0.001

*Significance levels across diagnostic categories; significance levels inside diagnostic categories pre-CRT vs post-CRT: †p<0.01; ‡p<0.005; §p<0.001; ¶p<0.05.

AV, atrioventricular; CHD, congenital heart disease; CRT, cardiac resynchronisation therapy; DCMP, dilated cardiomyopathy; EF, ejection fraction; FAC, fractional area of change; NS, non-significant; NYHA, New York Heart Association; SAVV, systemic atrioventricular valve; SVEDD, systemic ventricular end-diastolic dimension.