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. Author manuscript; available in PMC: 2009 Jun 23.
Published in final edited form as: Autoimmunity. 2004;37(6-7):445–451. doi: 10.1080/08916930400008524

FIGURE 4.

FIGURE 4

Serum levels of anti-cardiolipin antibodies. Upper panel: Serum anti-cardiolipin antibody titers at 15 and 17 weeks of age. Titers are calculated relative to an untreated mouse with the highest titer of anti-cardiolipin antibodies. Approximately 50% of untreated mice had an increase in titers between 15 and 17 weeks that was not observed in treated mice (Untreated vs. either 9 or 12 week treated mice p < 0.005 at 17 weeks). Lower panel: Serial measurement of IgG anti-cardiolipin levels in 9 week treated mice showed that they could be detected at low levels at 12 weeks of age but failed to increase further over time (*p < 0.01; ^p < 0.02). A similar pattern was observed in mice treated at 12 weeks (not shown).