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. Author manuscript; available in PMC: 2009 Jun 24.
Published in final edited form as: Vaccine. 2007 Jun 26;25(33):6158–6163. doi: 10.1016/j.vaccine.2007.06.012

Table 1.

Effects of UbE1267 DNA vaccination during the CRPV incubation period

Papilloma variable Results obtained at sites infected with the following CRPV dilutions:
Group a 1:50 1:150 1:450
Frequency b
 Vector DNA 15 / 15 15 / 15 15 / 15
 UbE1267 DNA 3 / 15 3 / 15 4 / 15
Time to detection c
 Vector DNA d < 21.0 ± 0.0 < 21.5 ± 0.5 < 21.5 ± 0.5
 UbE1267 DNA e 28.0 ± 4.0 35.0 ± 4.0 30.3 ± 2.3
a

Each group contained five rabbits.

b

Number of papilloma-forming sites/total number of infected sites. The papilloma frequency in the vaccinated rabbits is significantly lower than in the controls (P=0.0139).

c

Number of days from CRPV infection to the first detection of a palpable papilloma (mean ± standard error of the mean (SEM). Many papillomas in the vector control group actually formed earlier than 21 days, the first day that rabbits were examined after infection.

d

Data from the only vaccinee that formed papillomas (mean ± SEM).

e

Data from the only vaccinee that formed papillomas (mean ± SEM).