Abstract
Type F botulism was confirmed in a 54-year-old male with signs compatible with botulism who reported to the emergency unit of a hospital. Botulinal neurotoxin was detected in the patient's serum and fecal specimens, and a neurotoxigenic organism whose physiologic characteristics correspond to those of Clostridium baratii was isolated. The toxin produced by the isolate was neutralized by type F botulinal antitoxin and cross-neutralized with lower efficiency by type E antitoxin. The patient's food history was not suggestive of botulism, and it seems likely that the illness was due to colonization of the gut.
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Selected References
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- Aureli P., Fenicia L., Pasolini B., Gianfranceschi M., McCroskey L. M., Hatheway C. L. Two cases of type E infant botulism caused by neurotoxigenic Clostridium butyricum in Italy. J Infect Dis. 1986 Aug;154(2):207–211. doi: 10.1093/infdis/154.2.207. [DOI] [PubMed] [Google Scholar]
- Chia J. K., Clark J. B., Ryan C. A., Pollack M. Botulism in an adult associated with food-borne intestinal infection with Clostridium botulinum. N Engl J Med. 1986 Jul 24;315(4):239–241. doi: 10.1056/NEJM198607243150407. [DOI] [PubMed] [Google Scholar]
- Dowell V. R., Jr, McCroskey L. M., Hatheway C. L., Lombard G. L., Hughes J. M., Merson M. H. Coproexamination for botulinal toxin and clostridium botulinum. A new procedure for laboratory diagnosis of botulism. JAMA. 1977 Oct 24;238(17):1829–1832. [PubMed] [Google Scholar]
- Hall J. D., McCroskey L. M., Pincomb B. J., Hatheway C. L. Isolation of an organism resembling Clostridium barati which produces type F botulinal toxin from an infant with botulism. J Clin Microbiol. 1985 Apr;21(4):654–655. doi: 10.1128/jcm.21.4.654-655.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hoffman R. E., Pincomb B. J., Skeels M. R. Type F infant botulism. Am J Dis Child. 1982 Mar;136(3):270–271. doi: 10.1001/archpedi.1982.03970390084021. [DOI] [PubMed] [Google Scholar]
- Hughes J. M., Blumenthal J. R., Merson M. H., Lombard G. L., Dowell V. R., Jr, Gangarosa E. J. Clinical features of types A and B food-borne botulism. Ann Intern Med. 1981 Oct;95(4):442–445. doi: 10.7326/0003-4819-95-4-442. [DOI] [PubMed] [Google Scholar]
- McCroskey L. M., Hatheway C. L., Fenicia L., Pasolini B., Aureli P. Characterization of an organism that produces type E botulinal toxin but which resembles Clostridium butyricum from the feces of an infant with type E botulism. J Clin Microbiol. 1986 Jan;23(1):201–202. doi: 10.1128/jcm.23.1.201-202.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McCroskey L. M., Hatheway C. L. Laboratory findings in four cases of adult botulism suggest colonization of the intestinal tract. J Clin Microbiol. 1988 May;26(5):1052–1054. doi: 10.1128/jcm.26.5.1052-1054.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Yang K. H., Sugiyama H. Purification and properties of Clostridium botulinum type F toxin. Appl Microbiol. 1975 May;29(5):598–603. doi: 10.1128/am.29.5.598-603.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
