Abstract
The sensitivity and specificity of direct immunofluorescence microscopy performed on Pernasal swab specimens and compared with those of nasopharyngeal aspirates were 93 and 99%, respectively. Posterior nasopharyngeal swabs applied immediately to microscope slides allow a rapid and simple screening procedure for the diagnosis of acute respiratory syncytial virus infections.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Ahluwalia G., Embree J., McNicol P., Law B., Hammond G. W. Comparison of nasopharyngeal aspirate and nasopharyngeal swab specimens for respiratory syncytial virus diagnosis by cell culture, indirect immunofluorescence assay, and enzyme-linked immunosorbent assay. J Clin Microbiol. 1987 May;25(5):763–767. doi: 10.1128/jcm.25.5.763-767.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bell D. M., Walsh E. E., Hruska J. F., Schnabel K. C., Hall C. B. Rapid detection of respiratory syncytial virus with a monoclonal antibody. J Clin Microbiol. 1983 Jun;17(6):1099–1101. doi: 10.1128/jcm.17.6.1099-1101.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Cheeseman S. H., Pierik L. T., Leombruno D., Spinos K. E., McIntosh K. Evaluation of a commercially available direct immunofluorescent staining reagent for the detection of respiratory syncytial virus in respiratory secretions. J Clin Microbiol. 1986 Jul;24(1):155–156. doi: 10.1128/jcm.24.1.155-156.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Frayha H., Castriciano S., Mahony J., Chernesky M. Nasopharyngeal swabs and nasopharyngeal aspirates equally effective for the diagnosis of viral respiratory disease in hospitalized children. J Clin Microbiol. 1989 Jun;27(6):1387–1389. doi: 10.1128/jcm.27.6.1387-1389.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Freke A., Stott E. J., Roome A. P., Caul E. O. The detection of respiratory syncytial virus in nasopharyngeal aspirates: assessment, formulation, and evaluation of monoclonal antibodies as a diagnostic reagent. J Med Virol. 1986 Feb;18(2):181–191. doi: 10.1002/jmv.1890180210. [DOI] [PubMed] [Google Scholar]
- Hall C. B., Douglas R. G., Jr, Geiman J. M., Messner M. K. Nosocomial respiratory syncytial virus infections. N Engl J Med. 1975 Dec 25;293(26):1343–1346. doi: 10.1056/NEJM197512252932604. [DOI] [PubMed] [Google Scholar]
- Hall C. B., McBride J. T., Walsh E. E., Bell D. M., Gala C. L., Hildreth S., Ten Eyck L. G., Hall W. J. Aerosolized ribavirin treatment of infants with respiratory syncytial viral infection. A randomized double-blind study. N Engl J Med. 1983 Jun 16;308(24):1443–1447. doi: 10.1056/NEJM198306163082403. [DOI] [PubMed] [Google Scholar]
- Krasinski K., LaCouture R., Holzman R. S., Waithe E., Bonk S., Hanna B. Screening for respiratory syncytial virus and assignment to a cohort at admission to reduce nosocomial transmission. J Pediatr. 1990 Jun;116(6):894–898. doi: 10.1016/s0022-3476(05)80646-8. [DOI] [PubMed] [Google Scholar]
- MacDonald N. E., Hall C. B., Suffin S. C., Alexson C., Harris P. J., Manning J. A. Respiratory syncytial viral infection in infants with congenital heart disease. N Engl J Med. 1982 Aug 12;307(7):397–400. doi: 10.1056/NEJM198208123070702. [DOI] [PubMed] [Google Scholar]