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. 1992 Dec;30(12):3294–3297. doi: 10.1128/jcm.30.12.3294-3297.1992

Nosocomial transmission of rotavirus from patients admitted with diarrhea.

A Gaggero 1, L F Avendaño 1, J Fernández 1, E Spencer 1
PMCID: PMC270655  PMID: 1333491

Abstract

We studied the transmission of rotavirus (RV) in 950 patients under 2 years of age hospitalized for diarrhea in Santiago, Chile. Stool samples were collected every other day from all patients during their entire hospital stay. To trace nosocomial transmission, we mapped the ward at the time of detection of RV. Comparative study by polyacrylamide gel electrophoresis of 315 RV isolates (180 detected upon admission of patients and 135 attributed to nosocomial transmission) allowed the identification of 18 different electropherotypes. An electropherotype similar to that of a community-acquired case was found in the same room in 81% of nosocomial cases and in the ward in 92% of nosocomial cases. It was concluded that the infants admitted shedding RV are the major source of nosocomial transmission and there was not a RV strain that was particularly transmissible.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Avendaño L. F., Calderón A., Macaya J., Prenzel I., Duarte E. Rotavirus viral RNA electrophoresis in hospitalized infants with diarrhea in Santiago, Chile. Pediatr Res. 1982 Apr;16(4 Pt 1):329–330. doi: 10.1203/00006450-198204000-00018. [DOI] [PubMed] [Google Scholar]
  2. Avendaño L. F., Matamala I. Diagnóstico y cuantificación de la excreción de rotavirus mediante electroforesis del ARN viral. Rev Med Chil. 1988 Sep;116(9):853–857. [PubMed] [Google Scholar]
  3. Barraza P., Avendaño L. F., Spencer E., Calderón A., Prenzel I., Duarte E. Infección intrahospitalaria por rotavirus en lactantes, Santiago, Chile. Bol Oficina Sanit Panam. 1986 Oct;101(4):328–338. [PubMed] [Google Scholar]
  4. Champsaur H., Henry-Amar M., Goldszmidt D., Prevot J., Bourjouane M., Questiaux E., Bach C. Rotavirus carriage, asymptomatic infection, and disease in the first two years of life. II. Serological response. J Infect Dis. 1984 May;149(5):675–682. doi: 10.1093/infdis/149.5.675. [DOI] [PubMed] [Google Scholar]
  5. Clark J. D., Hill S. M., Phillips A. D. Investigation of hospital-acquired rotavirus gastroenteritis using RNA electrophoresis. J Med Virol. 1988 Nov;26(3):289–299. doi: 10.1002/jmv.1890260309. [DOI] [PubMed] [Google Scholar]
  6. Estes M. K., Graham D. Y., Dimitrov D. H. The molecular epidemiology of rotavirus gastroenteritis. Prog Med Virol. 1984;29:1–22. [PubMed] [Google Scholar]
  7. Fernández J., Sandino A. M., Pizarro J., Avendaño L. F., Pizarro J. M., Spencer E. Characterization of rotavirus electropherotypes excreted by symptomatic and asymptomatic infants. Epidemiol Infect. 1991 Feb;106(1):189–198. doi: 10.1017/s0950268800056557. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Nakagomi T., Akatani K., Ikegami N., Katsushima N., Nakagomi O. Occurrence of changes in human rotavirus serotypes with concurrent changes in genomic RNA electropherotypes. J Clin Microbiol. 1988 Dec;26(12):2586–2592. doi: 10.1128/jcm.26.12.2586-2592.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Nicolas J. C., Pothier P., Cohen J., Lourenco M. H., Thompson R., Guimbaud P., Chenon A., Dauvergne M., Bricout F. Survey of human rotavirus propagation as studied by electrophoresis of genomic RNA. J Infect Dis. 1984 May;149(5):688–693. doi: 10.1093/infdis/149.5.688. [DOI] [PubMed] [Google Scholar]
  10. Ruggeri F. M., Marziano M. L., Tinari A., Salvatori E., Donelli G. Four-year study of rotavirus electropherotypes from cases of infantile diarrhea in Rome. J Clin Microbiol. 1989 Jul;27(7):1522–1526. doi: 10.1128/jcm.27.7.1522-1526.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Spencer E. G., Avendaño L. F., García B. I. Analysis of human rotavirus mixed electropherotypes. Infect Immun. 1983 Feb;39(2):569–574. doi: 10.1128/iai.39.2.569-574.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Spencer E., Avendaño F., Araya M. Characteristics and analysis of electropherotypes of human rotavirus isolated in Chile. J Infect Dis. 1983 Jul;148(1):41–48. doi: 10.1093/infdis/148.1.41. [DOI] [PubMed] [Google Scholar]
  13. Steele A. D., Alexander J. J. Molecular epidemiology of rotavirus in black infants in South Africa. J Clin Microbiol. 1987 Dec;25(12):2384–2387. doi: 10.1128/jcm.25.12.2384-2387.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]

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