Abstract
In July and August 1981, five patients in the cardiac surgery unit of the Bristol Royal Infirmary developed septicemia caused by Morganella morganii, Proteus mirabilis, or both of these species. Three of the patients had serious wound infections, and three of the patients died. Typing of the M. morganii isolates by O-serotyping and of the P. mirabilis isolates by O-serotyping, proticine production and sensitivity, and the Dienes reaction confirmed cross infection by both species. Although M. morganii has been regarded as a relatively unimportant human pathogen in the past, it may prove to be an important cause of nosocomial infection in the future.
Full text
PDF




Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Adler J. L., Burke J. P., Finland M. Infection and antibiotic usage at Boston City Hospital, January 1970. Arch Intern Med. 1971 Mar;127(3):460–465. [PubMed] [Google Scholar]
- Adler J. L., Burke J. P., Martin D. F., Finland M. Proteus infections in a general hospital. II. Some clinical and epidemiological characteristis. With an analysis of 71 cases of proteus bacteremia. Ann Intern Med. 1971 Oct;75(4):531–536. doi: 10.7326/0003-4819-75-4-531. [DOI] [PubMed] [Google Scholar]
- Al-Jumaili I. J. Bacteriocine typing of Proteus. J Clin Pathol. 1975 Oct;28(10):784–787. doi: 10.1136/jcp.28.10.784. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Barrett F. F., Casey J. I., Finland M. Infections and antibiotic use among patients at Boston City Hospital, February, 1967. N Engl J Med. 1968 Jan 4;278(1):5–9. doi: 10.1056/NEJM196801042780102. [DOI] [PubMed] [Google Scholar]
- Burke J. P., Ingall D., Klein J. O., Gezon H. M., Finland M. Proteus mirabilis infections in a hospital nursery traced to a human carrier. N Engl J Med. 1971 Jan 21;284(3):115–121. doi: 10.1056/NEJM197101212840301. [DOI] [PubMed] [Google Scholar]
- Chow A. W., Taylor P. R., Yoshikawa T. T., Guze L. B. A nosocomial outbreak of infections due to multiply resistant Proteus mirabilis: role of intestinal colonization as a major reservoir. J Infect Dis. 1979 Jun;139(6):621–627. doi: 10.1093/infdis/139.6.621. [DOI] [PubMed] [Google Scholar]
- De Louvois J. Serotyping and the Dienes reaction on Proteus mirabilis from hospital infections. J Clin Pathol. 1969 May;22(3):263–268. doi: 10.1136/jcp.22.3.263. [DOI] [PMC free article] [PubMed] [Google Scholar]
- France D. R., Markham N. P. Epidemiological aspects of Proteus infections with particular reference to phage typing. J Clin Pathol. 1968 Jan;21(1):97–102. doi: 10.1136/jcp.21.1.97. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hickman F. W., Farmer J. J., 3rd Differentiation of Proteus mirabilis by bacteriophage typing and the Dienes reaction. J Clin Microbiol. 1976 Mar;3(3):350–358. doi: 10.1128/jcm.3.3.350-358.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
- LANYI B. Serological typing of Proteus strains from infantile enteritis and other sources. Acta Microbiol Acad Sci Hung. 1956;3(4):417–428. [PubMed] [Google Scholar]
- Marier R., Valenti A. J., Mardi J. A. Gram-negative endocarditis following cystoscopy. J Urol. 1978 Jan;119(1):134–137. doi: 10.1016/s0022-5347(17)57410-8. [DOI] [PubMed] [Google Scholar]
- Penner J. L., Hennessy J. N. O antigen grouping of Morganella morganii (Proteus morganii) by slide agglutination. J Clin Microbiol. 1979 Jul;10(1):8–13. doi: 10.1128/jcm.10.1.8-13.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Penner J. L., Hennessy J. N. Separate O-grouping schemes for serotyping clinical isolates of Proteus vulgaris and Proteus mirabilis. J Clin Microbiol. 1980 Sep;12(3):304–309. doi: 10.1128/jcm.12.3.304-309.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
- STORY P. Proteus infections in hospital. J Pathol Bacteriol. 1954 Jul;68(1):55–62. doi: 10.1002/path.1700680107. [DOI] [PubMed] [Google Scholar]
- Senior B. W. The Dienes phenomenon: identification of the determinants of compatibility. J Gen Microbiol. 1977 Oct;102(2):235–244. doi: 10.1099/00221287-102-2-235. [DOI] [PubMed] [Google Scholar]
- Senior B. W. The special affinity of particular types of Proteus mirabilis for the urinary tract. J Med Microbiol. 1979 Feb;12(1):1–8. doi: 10.1099/00222615-12-1-1. [DOI] [PubMed] [Google Scholar]
- Senior B. W. Typing of Proteus strains by proticine production and sensitivity. J Med Microbiol. 1977 Feb;10(1):7–17. doi: 10.1099/00222615-10-1-7. [DOI] [PubMed] [Google Scholar]
- Skirrow M. B. The dienes (mutual inhibition) test in the investigation of proteus infections. J Med Microbiol. 1969 Nov 4;2(4):471–477. doi: 10.1099/00222615-2-4-471. [DOI] [PubMed] [Google Scholar]
- Tucci V., Isenberg H. D. Hospital cluster epidemic with Morganella morganii. J Clin Microbiol. 1981 Nov;14(5):563–566. doi: 10.1128/jcm.14.5.563-566.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
- YOW E. M. Development of Proteus and Pseudomonas infections during antibiotic therapy. J Am Med Assoc. 1952 Jul 26;149(13):1184–1188. doi: 10.1001/jama.1952.02930300010003. [DOI] [PubMed] [Google Scholar]
