Abstract
A new fluorescent polarization immunoassay (Abbott Laboratories, Diagnostics Division, North Chicago, Ill.) was compared with a standard radioimmunoassay (American Diagnostics Corp., Newport Beach, Calif.) in 34 patients being treated with vancomycin. A total of 123 serum samples were divided and quantitatively analyzed for vancomycin by both assay methods. The results obtained indicated that the two assay methods are comparable (y = 1.01x - 0.81; r = 0.99).
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Selected References
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- Crossley K. B., Rotschafer J. C., Chern M. M., Mead K. E., Zaske D. E. Comparison of a radioimmunoassay and a microbiological assay for measurement of serum vancomycin concentrations. Antimicrob Agents Chemother. 1980 Apr;17(4):654–657. doi: 10.1128/aac.17.4.654. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Esposito A. L., Gleckman R. A. Vancomycin. A second look. JAMA. 1977 Oct 17;238(16):1756–1757. doi: 10.1001/jama.238.16.1756. [DOI] [PubMed] [Google Scholar]
- Fong K. L., Ho D. H., Bogerd L., Pan T., Brown N. S., Gentry L., Bodey G. P., Sr Sensitive radioimmunoassay for vancomycin. Antimicrob Agents Chemother. 1981 Jan;19(1):139–143. doi: 10.1128/aac.19.1.139. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McClain J. B., Bongiovanni R., Brown S. Vancomycin quantitation by high-performance liquid chromatography in human serum. J Chromatogr. 1982 Sep 10;231(2):463–466. doi: 10.1016/s0378-4347(00)81873-3. [DOI] [PubMed] [Google Scholar]
- Moellering R. C., Jr, Krogstad D. J., Greenblatt D. J. Vancomycin therapy in patients with impaired renal function: a nomogram for dosage. Ann Intern Med. 1981 Mar;94(3):343–346. doi: 10.7326/0003-4819-94-3-343. [DOI] [PubMed] [Google Scholar]
- Polk R. E., Espinel-Ingroff A., Lockridge R. In vitro evaluation of a vancomycin radioimmunoassay and observations on vancomycin pharmacokinetics in dialysis patients. Drug Intell Clin Pharm. 1981 Jan;15(1):15–20. doi: 10.1177/106002808101500103. [DOI] [PubMed] [Google Scholar]
- Ratcliff R. M., Mirelli C., Moran E., O'Leary D., White R. Comparison of five methods for the assay of serum gentamicin. Antimicrob Agents Chemother. 1981 Apr;19(4):508–512. doi: 10.1128/aac.19.4.508. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rotschafer J. C., Crossley K., Zaske D. E., Mead K., Sawchuk R. J., Solem L. D. Pharmacokinetics of vancomycin: observations in 28 patients and dosage recommendations. Antimicrob Agents Chemother. 1982 Sep;22(3):391–394. doi: 10.1128/aac.22.3.391. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rotschafer J. C., Morlock C., Strand L., Crossley K. Comparison of radioimmunoassay and enzyme immunoassay methods in determining gentamicin pharmacokinetic parameters and dosages. Antimicrob Agents Chemother. 1982 Oct;22(4):648–651. doi: 10.1128/aac.22.4.648. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Traber P. G., Levine D. P. Vancomycin Ototoxicity in patient with normal renal function. Ann Intern Med. 1981 Oct;95(4):458–460. doi: 10.7326/0003-4819-95-4-458. [DOI] [PubMed] [Google Scholar]
- Uhl J. R., Anhalt J. P. High performance liquid chromatographic assay of vancomycin in serum. Ther Drug Monit. 1979;1(1):75–83. doi: 10.1097/00007691-197901000-00008. [DOI] [PubMed] [Google Scholar]
- Walker C. N. Bioassay for determination of vancomycin in the presence of rifampin or aminoglycosides. Antimicrob Agents Chemother. 1980 Apr;17(4):730–731. doi: 10.1128/aac.17.4.730. [DOI] [PMC free article] [PubMed] [Google Scholar]