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. 1984 Jun;19(6):794–797. doi: 10.1128/jcm.19.6.794-797.1984

Use of absorbed antisera for demonstration of antigenic variation among strains of Legionella pneumophila serogroup 1.

B M Thomason, W F Bibb
PMCID: PMC271187  PMID: 6206087

Abstract

Antigenic typing of strains of Legionella pneumophila serogroup 1 (Lp1) has been shown to be useful in epidemiological studies of outbreaks of legionellosis. Selective absorption of rabbit antibodies produced against five strains of Lp1 resulted in the recognition of 17 somatic types among the 176 strains tested. A comparison was made of our results and those obtained by McKinney et al. (Zentralbl. Bakteriol. Parasitenkd. Infektionskr. Hyg. Abt. 1 Orig. Reihe A 255:91-95, 1983) and Joly et al. (J. Clin. Microbiol. 18:1040-1046, 1983), who used monoclonal antibodies to subgroup Lp1 strains. The results indicate that antigens are present in Lp1 strains that were undetected by either system. The data presented in this study may be helpful in selecting for the production of additional monoclonal or absorbed antibodies for diagnostic purposes or epidemiological studies.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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