Fig. 4.

VAST structure, guide and CORAL alignments between the eukaryotic translation factor 5A domain (cd04468; eIF5A) and the Hex1/S1-like RNA-binding domain (cd04469; S1_Hex1) are illustrated using sequence fragments from 1X6O and 1KHI and structure superpositions. The domains share a parent (EF- and S1-like RNA-binding domain) and 28% identity. Aligned positions in the reference alignments are underlined. The structure alignment is believed to be the most accurate. Misaligned regions in the guide and CORAL alignments are colored blue. RNA-binding sites are highlighted in yellow on both sequence and structure alignments. The structure superposition is colored red for identical residues, purple for other aligned residues and grey for unaligned residues.