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. 1984 Nov;20(5):874–876. doi: 10.1128/jcm.20.5.874-876.1984

Cryptosporidium spp., a frequent cause of diarrhea in Central Africa.

J Bogaerts, P Lepage, D Rouvroy, J Vandepitte
PMCID: PMC271463  PMID: 6210302

Abstract

Cryptosporidium oocysts were present in 20 (10.4%) of 193 Rwandese children and in 3 (3.0%) of 100 adults with diarrhea. In four of the children and in one adult, Cryptosporidium was associated with other enteric pathogens. The higher incidence of Cryptosporidium in diarrheic children was statistically significant. The parasite was not found in 94 formed stools submitted for parasitological examination. The mean age of the Cryptosporidium-positive children was 13.3 months. In four children, Cryptosporidium was associated with severe malnutrition. All of those required rehydration, and one child died as a direct consequence of severe diarrhea. The three adult patients showed no recognizable immunodeficiency, and their diarrhea resolved spontaneously. Staining with 1% safranin was not only more simple and rapid but also more sensitive than the modified Ziehl-Neelsen technique.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Anderson B. C., Donndelinger T., Wilkins R. M., Smith J. Cryptosporidiosis in a veterinary student. J Am Vet Med Assoc. 1982 Feb 15;180(4):408–409. [PubMed] [Google Scholar]
  2. Babb R. R., Differding J. T., Trollope M. L. Cryptosporidia enteritis in a healthy professional athlete. Am J Gastroenterol. 1982 Nov;77(11):833–834. [PubMed] [Google Scholar]
  3. Baxby D., Blundell N. Sensitive, rapid, simple methods for detecting Crysporidium in faeces. Lancet. 1983 Nov 12;2(8359):1149–1149. doi: 10.1016/s0140-6736(83)90669-4. [DOI] [PubMed] [Google Scholar]
  4. Casemore D. P., Jackson B. Sporadic cryptosporidiosis in children. Lancet. 1983 Sep 17;2(8351):679–679. doi: 10.1016/s0140-6736(83)92552-7. [DOI] [PubMed] [Google Scholar]
  5. Chandra R. K. Nutrition, immunity, and infection: present knowledge and future directions. Lancet. 1983 Mar 26;1(8326 Pt 1):688–691. doi: 10.1016/s0140-6736(83)91980-3. [DOI] [PubMed] [Google Scholar]
  6. Current W. L., Reese N. C., Ernst J. V., Bailey W. S., Heyman M. B., Weinstein W. M. Human cryptosporidiosis in immunocompetent and immunodeficient persons. Studies of an outbreak and experimental transmission. N Engl J Med. 1983 May 26;308(21):1252–1257. doi: 10.1056/NEJM198305263082102. [DOI] [PubMed] [Google Scholar]
  7. Garcia L. S., Bruckner D. A., Brewer T. C., Shimizu R. Y. Techniques for the recovery and identification of Cryptosporidium oocysts from stool specimens. J Clin Microbiol. 1983 Jul;18(1):185–190. doi: 10.1128/jcm.18.1.185-190.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Henriksen S. A., Pohlenz J. F. Staining of cryptosporidia by a modified Ziehl-Neelsen technique. Acta Vet Scand. 1981;22(3-4):594–596. doi: 10.1186/BF03548684. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Human cryptosporidiosis. N Engl J Med. 1983 Nov 24;309(21):1325–1327. doi: 10.1056/NEJM198311243092114. [DOI] [PubMed] [Google Scholar]
  10. Immunodeficiency and cryptosporidiosis. Demonstration at the Royal College of Physicians of London. Br Med J. 1980 Oct 25;281(6248):1123–1127. doi: 10.1136/bmj.281.6248.1123. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Jokipii L., Pohjola S., Jokipii A. M. Cryptosporidium: a frequent finding in patients with gastrointestinal symptoms. Lancet. 1983 Aug 13;2(8346):358–361. doi: 10.1016/s0140-6736(83)90341-0. [DOI] [PubMed] [Google Scholar]
  12. Jonas C., Deprez C., De Maubeuge J., Taelman H., Panzer J. M., Deltenre M. Cryptosporidium in patient with acquired immunodeficiency syndrome. Lancet. 1983 Oct 22;2(8356):964–964. doi: 10.1016/s0140-6736(83)90473-7. [DOI] [PubMed] [Google Scholar]
  13. Malebranche R., Arnoux E., Guérin J. M., Pierre G. D., Laroche A. C., Péan-Guichard C., Elie R., Morisset P. H., Spira T., Mandeville R. Acquired immunodeficiency syndrome with severe gastrointestinal manifestations in Haiti. Lancet. 1983 Oct 15;2(8355):873–878. doi: 10.1016/s0140-6736(83)90868-1. [DOI] [PubMed] [Google Scholar]
  14. Meisel J. L., Perera D. R., Meligro C., Rubin C. E. Overwhelming watery diarrhea associated with a cryptosporidium in an immunosuppressed patient. Gastroenterology. 1976 Jun;70(6):1156–1160. [PubMed] [Google Scholar]
  15. Miller R. A., Holmberg R. E., Jr, Clausen C. R. Life-threatening diarrhea caused by Cryptosporidium in a child undergoing therapy for acute lymphocytic leukemia. J Pediatr. 1983 Aug;103(2):256–259. doi: 10.1016/s0022-3476(83)80360-6. [DOI] [PubMed] [Google Scholar]
  16. Nime F. A., Burek J. D., Page D. L., Holscher M. A., Yardley J. H. Acute enterocolitis in a human being infected with the protozoan Cryptosporidium. Gastroenterology. 1976 Apr;70(4):592–598. [PubMed] [Google Scholar]
  17. Pitlik S. D., Fainstein V., Rios A., Guarda L., Mansell P. W., Hersh E. M. Cryptosporidial cholecystitis. N Engl J Med. 1983 Apr 21;308(16):967–967. doi: 10.1056/NEJM198304213081616. [DOI] [PubMed] [Google Scholar]
  18. Reese N. C., Current W. L., Ernst J. V., Bailey W. S. Cryptosporidiosis of man and calf: a case report and results of experimental infections in mice and rats. Am J Trop Med Hyg. 1982 Mar;31(2):226–229. doi: 10.4269/ajtmh.1982.31.226. [DOI] [PubMed] [Google Scholar]
  19. Sloper K. S., Dourmashkin R. R., Bird R. B., Slavin G., Webster A. D. Chronic malabsorption due to cryptosporidiosis in a child with immunoglobulin deficiency. Gut. 1982 Jan;23(1):80–82. doi: 10.1136/gut.23.1.80. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Stemmermann G. N., Hayashi T., Glober G. A., Oishi N., Frankel R. I. Cryptosporidiosis. Report of a fatal case complicated by disseminated toxoplasmosis. Am J Med. 1980 Oct;69(4):637–642. doi: 10.1016/0002-9343(80)90481-7. [DOI] [PubMed] [Google Scholar]
  21. Tzipori S., Angus K. W., Gray E. W., Campbell I. Vomiting and diarrhea associated with cryptosporidial infection. N Engl J Med. 1980 Oct 2;303(14):818–818. [PubMed] [Google Scholar]
  22. Tzipori S. Cryptosporidiosis in animals and humans. Microbiol Rev. 1983 Mar;47(1):84–96. doi: 10.1128/mr.47.1.84-96.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Tzipori S., Smith M., Birch C., Barnes G., Bishop R. Cryptosporidiosis in hospital patients with gastroenteritis. Am J Trop Med Hyg. 1983 Sep;32(5):931–934. doi: 10.4269/ajtmh.1983.32.931. [DOI] [PubMed] [Google Scholar]
  24. Weinstein L., Edelstein S. M., Madara J. L., Falchuk K. R., McManus B. M., Trier J. S. Intestinal cryptosporidiosis complicated by disseminated cytomegalovirus infection. Gastroenterology. 1981 Sep;81(3):584–591. [PubMed] [Google Scholar]
  25. Weisburger W. R., Hutcheon D. F., Yardley J. H., Roche J. C., Hillis W. D., Charache P. Cryptosporidiosis in an immunosuppressed renal-transplant recipient with IgA deficiency. Am J Clin Pathol. 1979 Sep;72(3):473–478. doi: 10.1093/ajcp/72.3.473. [DOI] [PubMed] [Google Scholar]

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