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(A) Knockdown specificity was examined using three αU84 derivative oligonucleotides. Mismatched nucleotides are underlined. (B) The putative guide sequences of U83 and U84 snoRNAs are shown. Mismatched nucleotides are underlined. αU84 sequence underscored by an arrow is complementary to the U84 guide sequence. (C) RPA for detection of U84 and U83 snoRNA.
