Table 3.

Barriers and motivators specific to willingness to participate in an HIV vaccine trial and representative quotations from participants

	Quotations from participants in willingness to participate focus groups
Barriers
1. Uncertainty about vaccine characteristics	“What would they inject me with?” (Latina) “Maybe they are afraid of needles.” (African American female)
2. Study demands	“I would prefer going once versus three times.” (African American male) “Less is always better.” (MSM)a
Motivators
1. Altruism	“They need someone to try the cure, to see if it works. I would do it because it would help them find a cure for this disease.” (Latino male) “I feel like if I’m participating in an HIV vaccine trial, possibly to help someone in the future, that’s why I would do it.” (Latina)
2. Free medical care/Insurance	“I think for some people there would have to be some kind of insurance. . .If I took the placebo and I had risky sex and came out positive. I would need some kind of insurance that I will be taken care of.” (MSM) “Will we have some health insurance? Will they take care of our health? There might be side effects. . .maybe our careers would be affected, too. It would be great having the support, and health care, we would be more at ease.” (Latina) “They should give health care and doctors - that way you can go somewhere and get checked if you don’t feel well.” (Latino MSM)
3. Monetary incentives	“You may have to spend a lot of money - paid visits are best.” (Latina) “Only if the money was right.” (Male IDU)b

^aMSM = men who have sex with men.

^bIDU = injection drug user.