Abstract
A total of 136 specimens were tested for the presence of herpes simplex virus by routine tissue culture and a commercial enzyme-linked immunosorbent assay (Ortho Diagnostic Systems, Inc.). Forty-six (33.8%) of the specimens were positive by tissue culture. The sensitivity and specificity of the commercial system were 69.6 and 93.3%, respectively. The commercial system was rapid and moderately specific but lacked the sensitivity necessary for direct specimen testing.
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- Corey L., Adams H. G., Brown Z. A., Holmes K. K. Genital herpes simplex virus infections: clinical manifestations, course, and complications. Ann Intern Med. 1983 Jun;98(6):958–972. doi: 10.7326/0003-4819-98-6-958. [DOI] [PubMed] [Google Scholar]
- Fayram S. L., Aarnaes S., de la Maza L. M. Comparison of cultureset to a conventional tissue culture-fluorescent-antibody technique for isolation and identification of herpes simplex virus. J Clin Microbiol. 1983 Jul;18(1):215–216. doi: 10.1128/jcm.18.1.215-216.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kibrick S. Herpes simplex infection at term. What to do with mother, newborn, and nursery personnel. JAMA. 1980 Jan 11;243(2):157–160. doi: 10.1001/jama.243.2.157. [DOI] [PubMed] [Google Scholar]
- Land S. A., Skurrie I. J., Gilbert G. L. Rapid diagnosis of herpes simplex virus infections by enzyme-linked immunosorbent assay. J Clin Microbiol. 1984 Jun;19(6):865–869. doi: 10.1128/jcm.19.6.865-869.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Morgan M. A., Smith T. F. Evaluation of an enzyme-linked immunosorbent assay for the detection of herpes simplex virus antigen. J Clin Microbiol. 1984 Jun;19(6):730–732. doi: 10.1128/jcm.19.6.730-732.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sewell D. L., Horn S. A., Dilbeck P. W. Comparison of Cultureset and Bartels Immunodiagnostics with conventional tissue culture for isolation and identification of herpes simplex virus. J Clin Microbiol. 1984 May;19(5):705–706. doi: 10.1128/jcm.19.5.705-706.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Warford A. L., Levy R. A., Rekrut K. A. Evaluation of a commercial enzyme-linked immunosorbent assay for detection of herpes simplex virus antigen. J Clin Microbiol. 1984 Sep;20(3):490–493. doi: 10.1128/jcm.20.3.490-493.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Whitley R. J., Nahmias A. J., Soong S. J., Galasso G. G., Fleming C. L., Alford C. A. Vidarabine therapy of neonatal herpes simplex virus infection. Pediatrics. 1980 Oct;66(4):495–501. [PubMed] [Google Scholar]