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Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1981 Aug;14(2):147–152. doi: 10.1128/jcm.14.2.147-152.1981

Comparison of enzyme-linked immunosorbent assay for acute measles with hemagglutination inhibition complement fixation, and fluorescent-antibody methods.

M B Kleiman, C K Blackburn, S E Zimmerman, M L French
PMCID: PMC271924  PMID: 7024302

Abstract

An enzyme-linked immunosorbent assay (ELISA) using commercially available reagents was compared with standard serological tests for determination of antibody titers in patients with acute measles. The measles-specific ELISA was as sensitive as complement fixation, hemagglutination inhibition, and indirect fluorescent-antibody methods. The ELISA method used was simple, sensitive, inexpensive, and reproducible and may conveniently be used in a small clinical laboratory.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Cherry J. D. The 'new' epidemiology of measles and rubella. Hosp Pract. 1980 Jul;15(7):49–57. doi: 10.1080/21548331.1980.11946629. [DOI] [PubMed] [Google Scholar]
  2. ENDERS J. F., McCARTHY K., MITUS A., CHEATHAM W. J. Isolation of measles virus at autopsy in cases of giant-cell pneumonia without rash. N Engl J Med. 1959 Oct 29;261:875–881. doi: 10.1056/NEJM195910292611801. [DOI] [PubMed] [Google Scholar]
  3. Fulginiti V. A., Helfer R. E. Atypical measles in adolescent siblings 16 years after killed measles virus vaccine. JAMA. 1980 Aug 22;244(8):804–806. [PubMed] [Google Scholar]
  4. Fulton R. E., Middleton P. J. Immunofluorescence in diagnosis of measles infections in children. J Pediatr. 1975 Jan;86(1):17–22. doi: 10.1016/s0022-3476(75)80698-6. [DOI] [PubMed] [Google Scholar]
  5. Kahane S., Goldstein V., Sarov I. Detection of IgG antibodies specific for measles virus by enzyme-linked immunosorbent assay (ELISA). Intervirology. 1979;12(1):39–46. doi: 10.1159/000149067. [DOI] [PubMed] [Google Scholar]
  6. Nieburg P. I., D'Angelo L. J., Herrmann K. L. Measles in patients suspected of having Rocky Mountain spotted fever. JAMA. 1980 Aug 22;244(8):808–809. [PubMed] [Google Scholar]
  7. Paule C. L., Bean J. A., Burmeister L. F., Isacson P. Postvaccine era measles epidemiology. JAMA. 1979 Apr 6;241(14):1474–1476. [PubMed] [Google Scholar]
  8. Voller A., Bartlett A., Bidwell D. E. Enzyme immunoassays with special reference to ELISA techniques. J Clin Pathol. 1978 Jun;31(6):507–520. doi: 10.1136/jcp.31.6.507. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Voller A., Bidwell D. E. Enzyme-immunoassays for antibodies in measles, cytomegalovirus infections and after rubella vaccination. Br J Exp Pathol. 1976 Apr;57(2):243–247. [PMC free article] [PubMed] [Google Scholar]

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