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. 1982 Mar;15(3):429–434. doi: 10.1128/jcm.15.3.429-434.1982

Indirect fluorescent-antibody technique for serological diagnosis of La Crosse (California) virus infections.

B J Beaty, J Casals, K L Brown, C B Gundersen, D Nelson, J T McPherson, W H Thompson
PMCID: PMC272112  PMID: 7042745

Abstract

A clinically relevant indirect fluorescent-antibody technique (IFA) was developed for the serological diagnosis of La Crosse virus infections. The IFA (67%) was as sensitive as the hemagglutination inhibition (58%) and neutralization (58%) tests in the detection of antibodies in acute-phase specimens. Immunoglobulin M antibodies were detected by the IFA test in 48% (11 of 23) of these specimens. Diagnostically significant increases in IFA titer were detected in 86% (19 of 22) of the paired samples. Antibodies were detectable in some patients 7 years after infection; however, the IFA test was not as sensitive as the other two tests in the detection of previous infections.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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