Abstract
Over a 3-year period, 96% of systemic infections in children caused by Haemophilus influenzae were of serotype b. Of 346 invasive infections, 15 (4%) were caused by non-type b H. influenzae. The monthly prevalence of ampicillin resistance in all isolates was highly variable (0 to 63%). Ampicillin resistance in H. influenzae causing invasive disease occurred in 13% of non-type b and 21.8% of type b isolates. There was no significant difference (x2 - 0.21; p greater than 0.10) in the rate of ampicillin resistance between type b and non-type b H. influenzae causing systemic illness in children over a 3-year period.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bell S. M., Plowman D. Mechanisms of ampicillin resistance in Haemophilus influenzae from respiratory tract. Lancet. 1980 Feb 9;1(8163):279–280. doi: 10.1016/s0140-6736(80)90778-3. [DOI] [PubMed] [Google Scholar]
- Escamilla J. Susceptibility of Haemophilus influenza to ampicillin as determined by use of a modified, one-minute beta-lactamase test. Antimicrob Agents Chemother. 1976 Jan;9(1):196–198. doi: 10.1128/aac.9.1.196. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Greene G. R. Meningitis due to Haemophilus influenzae other than type b: case report and review. Pediatrics. 1978 Dec;62(6):1021–1025. [PubMed] [Google Scholar]
- Kilian M. A rapid method for the differentiation of Haemophilus strains. The porphyrin test;. Acta Pathol Microbiol Scand B Microbiol Immunol. 1974 Dec;82(6):835–842. doi: 10.1111/j.1699-0463.1974.tb02381.x. [DOI] [PubMed] [Google Scholar]
- Kilian M. A taxonomic study of the genus Haemophilus, with the proposal of a new species. J Gen Microbiol. 1976 Mar;93(1):9–62. doi: 10.1099/00221287-93-1-9. [DOI] [PubMed] [Google Scholar]
- Lerman S. J., Brunken J. M., Bollinger M. Prevalence of ampicillin-resistant strains of Haemophilus influenzae causing systemic infection. Antimicrob Agents Chemother. 1980 Sep;18(3):474–475. doi: 10.1128/aac.18.3.474. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Myhre E. B. Typing of Haemophilus influenzae by counterimmunoelectrophoresis. Acta Pathol Microbiol Scand B Microbiol Immunol. 1974 Apr;82(2):164–166. doi: 10.1111/j.1699-0463.1974.tb02308.x. [DOI] [PubMed] [Google Scholar]
- Syriopoulou V., Scheifele D., Smith A. L., Perry P. M., Howie V. Increasing incidence of ampicillin resistance in Hemophilus influenzae. J Pediatr. 1978 Jun;92(6):889–892. doi: 10.1016/s0022-3476(78)80354-0. [DOI] [PubMed] [Google Scholar]
- Wallace R. J., Jr, Musher D. M., Septimus E. J., McGowan J. E., Jr, Quinones F. J., Wiss K., Vance P. H., Trier P. A. Haemophilus influenzae infections in adults: characterization of strains by serotypes, biotypes, and beta-lactamase production. J Infect Dis. 1981 Aug;144(2):101–106. doi: 10.1093/infdis/144.2.101. [DOI] [PubMed] [Google Scholar]
- Ward J. I., Tsai T. F., Filice G. A., Fraser D. W. Prevalence of ampicillin- and chloramphenicol-resistant strains of Haemophilus influenzae causing meningitis and bacteremia: national survey of hospital laboratories. J Infect Dis. 1978 Sep;138(3):421–424. doi: 10.1093/infdis/138.3.421. [DOI] [PubMed] [Google Scholar]
- Weinstein L. Type b haemophilus influenzae infections in adults. N Engl J Med. 1970 Jan 22;282(4):221–222. doi: 10.1056/NEJM197001222820411. [DOI] [PubMed] [Google Scholar]